Results 151 to 160 of about 16,631 (311)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Editing (and) individuation

open access: yes, 2012
This essay will explore aspects of Bernard Stiegler's theorisation of film editing as the construction of a flux of perceptual experience at the heart of the industrialisation of attention characteristic of modern and contemporary technocultures.
Crogan, Patrick
core  

Sparse Spatial Scaffolding for Visual Working Memory. [PDF]

open access: yesJ Neurosci
Liu B   +4 more
europepmc   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Relative values: resisting desire and individuation in Barbara Garlaschelli's 'Alice nell'ombra' and 'Sorelle'

open access: yes, 2003
Barbara Garlaschelli (Milan, 1965), a successful author of literature for adolescents, editor of children's series and publishing consultant, has recently received acclaim in Italy as one of the most interesting new voices in noir fiction, with two ...
Di Ciolla, Nicoletta
core  

The frequency-dependent effects of primary hand motor cortex stimulation on volitional finger movement. [PDF]

open access: yesClin Neurophysiol Pract
Taquet L   +8 more
europepmc   +1 more source

Towards Musical Individuation

open access: yesVoices, 2008
Dong Min Kim
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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