Results 101 to 110 of about 178,765 (288)

Dumbbell‐Structured Plasmonic‐Enhanced Optical Nanoprobes Boosting Photo‐Magnetic‐Acoustic Multimodal Imaging‐Guided Photodynamic‐Photothermal Synergistic Treatment and Immunogenic Death in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
This study reports a novel rationally‐designed optical nanoprobe based on dumbbell‐shaped mesoporous silica‐coated gold nanorods, loaded with rare‐earth oxides, photosensitizers, and tumor‐targeted peptides, enabling plasmonic‐enhanced multimodal imaging and PTT‐PDT synergy.
Baikang Zhuang, Yubiao Yang, Wen Han, Yi Tang, Chengxin Yao, Fuli Zhao, Wenxiao Fang, Jinjie Li, Xiaolan Huo, Yiqian An, Yuanzhi Shao, Botao Gao, Jinchang Yin   +12 more
wiley   +1 more source

Indole-2-carboxamide-based MmpL3 Inhibitors Show Exceptional Antitubercular Activity in an Animal Model of Tuberculosis Infection [PDF]

, 2016
Our team had previously identified certain indolecarboxamides that represented a new chemical scaffold that showed promising anti-TB activity at both an in vitro and in vivo level.
Haidan Guo (185242), Shichun Lun (85141), Oluseye K. Onajole (1343400), Benjamin Merenbloom (2849507), William R. Bishai (149943), Alan P. Kozikowski (1343391), Jozef Stec (1276773), Giulio Vistoli (1408930)   +7 more
core   +1 more source

Antiplasmodial Bis-Indole Alkaloids from the Bark of Flindersia pimenteliana [PDF]

, 2020
Three new (1-3) and 2 known (4-5) bis-indole alkaloids were identified from the bark of Flindersia pimenteliana (Rutaceae). The structures of 1-3 were elucidated on the basis of their (+)-HRESESIMS and 2D NMR spectroscopic data.
Lucantoni, Leonardo, Carroll, Anthony R, Avery, Vicky M, Robertson, Luke P   +3 more
core   +1 more source

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

Advanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang, Lei Ye, Peigen Xie, Tao Song, Jian Chen, Heng Zhao, Zhengshan Liu, Xi Chen, Jianing Ding, Xintian Ding, Ao Shao, Miaomiao Wu, Fengdong Zhao, Siyue Tao, Tao You   +14 more
wiley   +1 more source

Antistaphylococcal evaluation of indole–naphthalene hybrid analogs [PDF]

, 2019
Kerolos Ashraf,1 Kaveh Yasrebi,1 Emmanuel Tola Adeniyi,2 Tobias Hertlein,2 Knut Ohlsen,2 Michael Lalk,3 Frank Erdmann,1 Andreas Hilgeroth1 1Institute of Pharmacy, Martin Luther University Halle-Wittenberg, Halle, Germany; 2Institute of Molecular ...
Ohlsen K, Erdmann F, Hilgeroth A, Lalk M, Ashraf K, Adeniyi ET, Hertlein T, Yasrebi K   +7 more
core  

Hydrothermal Humification of Biomass for Circular Carbon Management in Sustainable Agro‐Ecosystems

Advanced Science, EarlyView.
This article provides a comprehensive overview of biomass hydrothermal humification for building sustainable agro‐ecosystems. It examines the chemical transformation mechanisms and the functional benefits of the produced humic acids in soil remediation.
Ziyun Liu, Zonglu Yao, Yuanhui Zhang, Huiyan Zhang, Lixin Zhao   +4 more
wiley   +1 more source

Physiological Response of Corynebacterium glutamicum to Indole

Microorganisms, 2020
The aromatic heterocyclic compound indole is widely spread in nature. Due to its floral odor indole finds application in dairy, flavor, and fragrance products.
Tatjana Walter, Kareen H. Veldmann, Susanne Götker, Tobias Busche, Christian Rückert, Arman Beyraghdar Kashkooli, Jannik Paulus, Katarina Cankar, Volker F. Wendisch   +8 more
doaj   +1 more source

​Indole is an essential herbivore-induced volatile priming signal in maize [PDF]

, 2015
Herbivore-induced volatile organic compounds prime non-attacked plant tissues to respond more strongly to subsequent attacks. However, the key volatiles that trigger this primed state remain largely unidentified.
Hao Xu, Xu, Hao, Nathalie Veyrat, Erb, M., Turlings, Ted C. J., Monika Frey, Jurriaan Ton, Frey, Monika, Robert, C.A.M., Christelle A. M. Robert, Matthias Erb, Ton, Jurriaan, Erb, Matthias, Veyrat, N., Veyrat, Nathalie, Robert, Christelle A. M., Xu, H., Ted C. J. Turlings, Frey, M., Ton, J., Turlings, T.C.J.   +20 more
core   +1 more source

Brown Adipocyte Sheets Alleviate Myocardial Ischemia–Reperfusion Injury Through NRG4–ErbB4–Dependent Ferroptosis Inhibition

Advanced Science, EarlyView.
Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun, Yuting Liu, Jingbo Zhang, Takuji Kawamura, Junjun Li, Li Liu, Shigeru Miyagawa   +6 more
wiley   +1 more source

Spiro Indane-Based Phosphine-Oxazolines as Highly Efficient P,N Ligands for Enantioselective Pd-Catalyzed Allylic Alkylation of Indoles and Allylic Etherification

Molecules, 2019
A series of indane-based phosphine-oxazoline ligands with a spirocarbon stereogenic center were examined for palladium-catalyzed asymmetric allylic alkylation of indoles. Under optimized conditions, high yields (up to 98%) and enantioselectivities (up to
Zhongxuan Qiu, Rui Sun, Kun Yang, Dawei Teng   +3 more
doaj   +1 more source