Nutritional Influences on Skatole Formation and Skatole Metabolism in the Pig
Animals, 2012 Skatole is a tryptophan (TRP) metabolite with fecal odor. Together with the testicular steroid androstenone it is regarded as a main determinant of boar taint, even if elevated concentrations of skatole occur occasionally in gilts and barrows.
Ulrike Weiler, Raffael Wesoly
exaly +4 more sources
Ecotoxicology and Environmental Safety, 2023 Skatole is a typical malodor compound in animal wastes. Several skatole-degrading bacterial strains have been obtained, whereas the molecular response of strains to skatole stress has not been well elucidated.
Qiao Ma
exaly +4 more sources
Advances in microbial degradation of skatole: A review [PDF]
Current Research in Microbial SciencesIn recent years, foul odors have led to widespread public complaints and have become a prominent issue in the field of environmental protection. Skatole, as one of the important components of foul odors, is a decomposition product of tryptophan in the ...
Bingjie Xu +6 more
doaj +3 more sources
A novel and evolutionarily distinct flavoprotein monooxygenase drives skatole degradation in Rhodococcus [PDF]
Applied and Environmental MicrobiologySkatole (3-methylindole), a persistent and toxic N-heterocyclic aromatic pollutant, poses significant bioremediation challenges due to poorly defined biodegradation processes.
Nan Meng +6 more
doaj +2 more sources
Breed-dependent differences in gut microbiota linked to indole and skatole levels in Hezuo and DLY pigs [PDF]
BMC MicrobiologyBackgroud Indole and skatole are major odorous compounds generated in pig farms and their emissions affect the sustainable development of pig industry seriously.
Xiaoli Gao, Shengwei Zhang, Qiaoli Yang
doaj +2 more sources
Indole-3-Acetic Acid as a Putative Selective AhR Modulator Counteracts Skatole-Induced Dual-Hit Toxicity in Colorectal Cancer Cells [PDF]
ToxinsThe rising incidence of colorectal cancer (CRC) in modernized societies is linked to diet-induced dysbiosis, characterized by a critical metabolic divergence: the depletion of protective indole-3-acetic acid (IAA) concurrent with the accumulation of ...
Chihiro Takei, Hidehisa Shimizu
doaj +2 more sources
Effects of Saccharomyces cerevisiae on the regulation of skatole, microorganisms, and tryptophan metabolites in vitro fermentation of pig [PDF]
Microbiology SpectrumSkatole (3-methylindole), one of the most malodorous compounds from swine manure, poses serious risks to animal, human, and environmental health. Therefore, it has become a serious concern in livestock farming.
Xiaoli Gao +4 more
doaj +2 more sources
Skatole Alleviates Osteoarthritis by Reprogramming Macrophage Polarization and Protecting Chondrocytes [PDF]
ResearchOsteoarthritis (OA) is the most prevalent joint disease, yet effective disease-modifying OA drugs (DMOADs) remain elusive. Targeting macrophage polarization has emerged as a promising avenue for OA treatment.
Weiyun Wang +17 more
doaj +2 more sources
Molecular Analysis of Indole and Skatole Decomposition Metabolism in Acinetobacter piscicola p38 Utilizing Biochemical and Omics Approaches [PDF]
MicroorganismsIndole and skatole (3-methylindole, C9H9N) are common nitrogen-containing heterocyclic pollutants found in waste, wastewater treatment plants, and public restrooms and are the most notorious compounds in animal feces.
Zhonghao Wang +11 more
doaj +2 more sources
Indole-3-Acetic Acid and Skatole Exert Opposing Effects on MDR1 Proteostasis in Human Colonic Epithelial Cells: A Molecular Basis for the Gut Microbial Metabolic Switch [PDF]
Journal of XenobioticsThe escalating consumption of red meat is a potent environmental risk factor for inflammatory bowel disease (IBD), which is characterized by compromised expression of the xenobiotic transporter P-glycoprotein (MDR1/ABCB1). While gut microbiota metabolize
Kazuma Naito +3 more
doaj +2 more sources