Nutritional Influences on Skatole Formation and Skatole Metabolism in the Pig
Animals, 2012 Skatole is a tryptophan (TRP) metabolite with fecal odor. Together with the testicular steroid androstenone it is regarded as a main determinant of boar taint, even if elevated concentrations of skatole occur occasionally in gilts and barrows.
Ulrike Weiler, Raffael Wesoly
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Advances in microbial degradation of skatole: A review [PDF]
Current Research in Microbial SciencesIn recent years, foul odors have led to widespread public complaints and have become a prominent issue in the field of environmental protection. Skatole, as one of the important components of foul odors, is a decomposition product of tryptophan in the ...
Bingjie Xu +6 more
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A novel and evolutionarily distinct flavoprotein monooxygenase drives skatole degradation in Rhodococcus [PDF]
Applied and Environmental MicrobiologySkatole (3-methylindole), a persistent and toxic N-heterocyclic aromatic pollutant, poses significant bioremediation challenges due to poorly defined biodegradation processes.
Nan Meng +6 more
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Ecotoxicology and Environmental Safety, 2023 Skatole is a typical malodor compound in animal wastes. Several skatole-degrading bacterial strains have been obtained, whereas the molecular response of strains to skatole stress has not been well elucidated.
Yujie Li +5 more
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Long‐Term Changes in Olfactory Threshold During Rehabilitation After Total Laryngectomy: A Preliminary Study [PDF]
Laryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.In patients who underwent laryngectomy, olfactory thresholds recovered earlier, while identification abilities recovered later. Recovery speed varied by odor, with faster recovery for odors with physiological significance like putrid smells. ABSTRACT Objectives This study aimed to evaluate the time‐dependent changes in olfactory threshold and ...
Yumi Yamaguchi +9 more
wiley +2 more sources
Microbiome‐Based Clustering Identifies Glycemic Control‐Related Subtypes in Youth With Recent‐Onset Type 1 Diabetes [PDF]
MedComm, Volume 7, Issue 4, April 2026.Microbiome‐based clustering investigated possible glycemic control‐related endotypes in youth with recent‐onset T1D, and found a potential role of Bacteroides and skatole production in glycemic control. This study offers novel perspectives on the influence of intestinal microbes and its metabolites in T1D heterogeneity and lays a foundation for future ...
Huiling Tan +13 more
wiley +2 more sources
Indole-3-Acetic Acid as a Putative Selective AhR Modulator Counteracts Skatole-Induced Dual-Hit Toxicity in Colorectal Cancer Cells [PDF]
ToxinsThe rising incidence of colorectal cancer (CRC) in modernized societies is linked to diet-induced dysbiosis, characterized by a critical metabolic divergence: the depletion of protective indole-3-acetic acid (IAA) concurrent with the accumulation of ...
Chihiro Takei, Hidehisa Shimizu
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Effects of Saccharomyces cerevisiae on the regulation of skatole, microorganisms, and tryptophan metabolites in vitro fermentation of pig [PDF]
Microbiology SpectrumSkatole (3-methylindole), one of the most malodorous compounds from swine manure, poses serious risks to animal, human, and environmental health. Therefore, it has become a serious concern in livestock farming.
Xiaoli Gao +4 more
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Molecular Analysis of Indole and Skatole Decomposition Metabolism in Acinetobacter piscicola p38 Utilizing Biochemical and Omics Approaches [PDF]
MicroorganismsIndole and skatole (3-methylindole, C9H9N) are common nitrogen-containing heterocyclic pollutants found in waste, wastewater treatment plants, and public restrooms and are the most notorious compounds in animal feces.
Zhonghao Wang +11 more
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Skatole Alleviates Osteoarthritis by Reprogramming Macrophage Polarization and Protecting Chondrocytes [PDF]
ResearchOsteoarthritis (OA) is the most prevalent joint disease, yet effective disease-modifying OA drugs (DMOADs) remain elusive. Targeting macrophage polarization has emerged as a promising avenue for OA treatment.
Weiyun Wang +17 more
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