Results 31 to 40 of about 3,869 (216)

The Effect of Dietary Helianthus tuberosus L. on the Populations of Pig Faecal Bacteria and the Prevalence of Skatole

Animals, 2020
Jerusalem artichoke contains inulin polysaccharide, which has prebiotic effects and influences the microbiota of the digestive tract. The addition of Jerusalem artichoke in boar diets may decrease the content of skatole and indole, which are the main ...
Monika Okrouhlá, Jaroslav Čítek, Roman Švejstil, Kateřina Zadinová, Kamila Pokorná, Daniela Urbanová, Roman Stupka   +6 more
doaj   +2 more sources

End-product inhibition of skatole-metabolising enzymes CYP1A, CYP2A19 and CYP2E1 in porcine and piscine hepatic microsomes

Toxicology Letters, 2019
The hepatic cytochrome p450 enzymes 1 A, 2A19 and 2E1 is very important for the elimination of skatole from the body of pigs. Impaired skatole metabolism, results in skatole accumulation, which give rise to off flavor of the meat.
Sveriges lantbruksuniversitet., Zamaratskaia, Galia,, Burkina, Viktoriia,   +2 more
core   +2 more sources

Microbiome-Based Clustering Identifies Glycemic Control-Related Subtypes in Youth With Recent-Onset Type 1 Diabetes. [PDF]

MedComm (2020)
Microbiome‐based clustering investigated possible glycemic control‐related endotypes in youth with recent‐onset T1D, and found a potential role of Bacteroides and skatole production in glycemic control. This study offers novel perspectives on the influence of intestinal microbes and its metabolites in T1D heterogeneity and lays a foundation for future ...
Tan H, Ding Y, Gu Z, Wang X, Wang J, Wei T, Zhang X, Pan L, Shi Y, Chang S, Guo C, Weng J, Zheng X, Yue T.   +13 more
europepmc   +2 more sources

Long-Term Changes in Olfactory Threshold During Rehabilitation After Total Laryngectomy: A Preliminary Study. [PDF]

Laryngoscope Investig Otolaryngol
In patients who underwent laryngectomy, olfactory thresholds recovered earlier, while identification abilities recovered later. Recovery speed varied by odor, with faster recovery for odors with physiological significance like putrid smells. ABSTRACT Objectives This study aimed to evaluate the time‐dependent changes in olfactory threshold and ...
Yamaguchi Y, Umezaki T, Murakami D, Murakami T, Kikuchi Y, Sato N, Sawatsubashi M, Adachi K, Matsuo M, Nakagawa T.   +9 more
europepmc   +2 more sources

Preliminary Test of the Reduction Capacity for the Intestinal Adsorption of Skatole and Indole in Weaning Piglets by Pure and Coated Charcoal

Animals, 2021
To reduce the risk of boar taint, intact male piglets are immuno- or surgically castrated. One alternative is reducing skatole by adding skatole reducing or adsorbing substances to the boars’ diet.
Franziska Witte, Aleksandar Pajic, Florian Menger, Igor Tomasevic, Dana Carina Schubert, Christian Visscher, Nino Terjung   +6 more
doaj   +1 more source

Olsenella scatoligenes-derived skatole promotes smooth muscle cell proliferation and migration to aggravate atherosclerosis. [PDF]

ISME J
Coronary artery disease (CAD) remains the leading cause of mortality and morbidity globally. The gut microbiota has been implicated in the development of CAD through unclear mechanisms.
Zhao Y, Chen J, Zhu S, Xu Y, Zhu J, Yang J, Zhou W, Yang Y, Lin M, Chen Q, Xia M, Chen Y, Liu Y.   +12 more
europepmc   +2 more sources

Identification of the novel candidate genes and variants in boar liver tissues with divergent skatole levels using RNA deep sequencing. [PDF]

PLoS ONE, 2013
Boar taint is the unpleasant odour of meat derived from non-castrated male pigs, caused by the accumulation of androstenone and skatole in fat. Skatole is a tryptophan metabolite produced by intestinal bacteria in gut and catabolised in liver. Since boar
Asep Gunawan, Sudeep Sahadevan, Mehmet Ulas Cinar, Christiane Neuhoff, Christine Große-Brinkhaus, Luc Frieden, Dawit Tesfaye, Ernst Tholen, Christian Looft, Dessie Salilew Wondim, Michael Hölker, Karl Schellander, Muhammad Jasim Uddin   +12 more
doaj   +1 more source

Isolable Cysteine Sulfenyl Iodide: Stabilization by a Molecular Cradle, Crystal Structure, and Biologically Relevant Reactivity. [PDF]

Chembiochem
An isolable cysteine sulfenyl iodide (Cys–SI) stabilized by a molecular cradle is reported. X‐ray analysis and reactivity studies reveal hydrolysis to sulfenic acid, electrophilic substitution with indoles, and high reactivity toward amines and dimedone, providing direct evidence for long‐standing proposals on iodine‐mediated protein modification ...
Otaka S, Sano T, Sase S, Kuwano S, Goto K.   +4 more
europepmc   +2 more sources

Change in fat skatole and indole content in lambs switched from a concentrate-based diet indoors to alfalfa grazing for various durations before slaughter.

Meat Science, 2023
Meat from lambs fattened on alfalfa is at risk of excessive pastoral flavours due to high levels of in-fat volatile indolic compounds (especially, skatole). Skatole has also been identified as a potential marker of interest for authenticating pasture-fed
S. Prache, L. Rey-Cadilhac, A. Prunier
semanticscholar   +1 more source

Effect of Different Coffee Brews on Tryptophan Metabolite-Induced Cytotoxicity in HT-29 Human Colon Cancer Cells

Antioxidants, 2022
Coffee consumption positively influences colon health. Conversely, high levels of tryptophan metabolites such as skatole released from intestinal putrefactive fermentation in the presence of excessive dietary animal protein intake, and gut microbiota ...
Luigi Castaldo, Marianna Toriello, Luana Izzo, Raffaele Sessa, Sonia Lombardi, Silvia Trombetti, Yelko Rodríguez-Carrasco, Alberto Ritieni, Michela Grosso   +8 more
doaj   +1 more source