Animals, 2021 To reduce the risk of boar taint, intact male piglets are immuno- or surgically castrated. One alternative is reducing skatole by adding skatole reducing or adsorbing substances to the boars’ diet.
Franziska Witte +6 more
doaj +1 more source
Long-Term Changes in Olfactory Threshold During Rehabilitation After Total Laryngectomy: A Preliminary Study. [PDF]
Laryngoscope Investig OtolaryngolIn patients who underwent laryngectomy, olfactory thresholds recovered earlier, while identification abilities recovered later. Recovery speed varied by odor, with faster recovery for odors with physiological significance like putrid smells. ABSTRACT Objectives This study aimed to evaluate the time‐dependent changes in olfactory threshold and ...
Yamaguchi Y +9 more
europepmc +2 more sources
Skatole (3-Methylindole) Is a Partial Aryl Hydrocarbon Receptor Agonist and Induces CYP1A1/2 and CYP1B1 Expression in Primary Human Hepatocytes. [PDF]
PLoS ONE, 2016 Skatole (3-methylindole) is a product of bacterial fermentation of tryptophan in the intestine. A significant amount of skatole can also be inhaled during cigarette smoking.
Martin Krøyer Rasmussen +4 more
doaj +1 more source
Microbiome-Based Clustering Identifies Glycemic Control-Related Subtypes in Youth With Recent-Onset Type 1 Diabetes. [PDF]
MedComm (2020)Microbiome‐based clustering investigated possible glycemic control‐related endotypes in youth with recent‐onset T1D, and found a potential role of Bacteroides and skatole production in glycemic control. This study offers novel perspectives on the influence of intestinal microbes and its metabolites in T1D heterogeneity and lays a foundation for future ...
Tan H +13 more
europepmc +2 more sources
, 2002 The relationships between the level of skatole in backfat, the rate of skatole metabolism in isolated liver microsomes,hepatic cytochrome P450IIE1 content and mRNA levels were investigated in Large White✕ Landrace (LW) and the Meishan✕ Landrace (M ...
Wood, J. D. +3 more
core +5 more sources
The use of sugar beet pulp in pig diet to control skatole analysed by HPLC quantification method [PDF]
Scientia Agricola, 2023 This study aimed to determine the efficacy of a finishing diet added with sugar beet pulp to reduce backfat skatole of entire male pigs, using the optimised high-performance liquid chromatographic (HPLC) method.
Ricardo Pereira Pinto +5 more
doaj +1 more source
Identification of the novel candidate genes and variants in boar liver tissues with divergent skatole levels using RNA deep sequencing. [PDF]
PLoS ONE, 2013 Boar taint is the unpleasant odour of meat derived from non-castrated male pigs, caused by the accumulation of androstenone and skatole in fat. Skatole is a tryptophan metabolite produced by intestinal bacteria in gut and catabolised in liver. Since boar
Asep Gunawan +12 more
doaj +1 more source
Antioxidants, 2022 Coffee consumption positively influences colon health. Conversely, high levels of tryptophan metabolites such as skatole released from intestinal putrefactive fermentation in the presence of excessive dietary animal protein intake, and gut microbiota ...
Luigi Castaldo +8 more
doaj +1 more source
IMPLEMENTATION OF GENOMIC INFORMATION IN SELECTION OF BOARS ON SKATOLE AND ANDROSTENONE CONCENTRATIONS [PDF]
Poljoprivreda, 2015 Genomic predictors offer an opportunity to overcome the limitations of classical selection against boar taint, and this study evaluated different approaches to obtain such predictors. Samples from 941 pigs were included in a design which was dominated by
Boris Lukić
doaj +1 more source
In vivo effect of dried chicory root (Cichorium intybus L.) on xenobiotica metabolising cytochrome P450 enzymes in porcine liver [PDF]
, 2011 Cytochrome P450 (CYP) enzymes are widely studied for their involvement in metabolism of drugs and endogenous compounds. In porcine liver, CYP1A2,2Aand 2E1 are important for the metabolism of skatole.Feeding chicory roots to pigs is known to decrease the ...
Martin Krøyer Rasmussen +7 more
core +1 more source