Results 71 to 80 of about 178,765 (288)

Diastereoselective Indole-Dearomative Cope Rearrangements by Compounding Minor Driving Forces. [PDF]

open access: yes, 2022
Reported herein is the discovery of a diastereoselective indole-dearomative Cope rearrangement. A suite of minor driving forces (substrate destabilizing effects; product stabilizing effects) are what promote this otherwise unfavorable dearomatization ...
Subhadip, De   +6 more
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Novel approach to bis(indolyl)methanes using nickel nanoparticles as a reusable catalyst under solvent-free conditions [PDF]

open access: yesJournal of the Serbian Chemical Society, 2013
A nanosized Nickel as catalyst has been developed for the electrophilic substitution reactions of indole with variousaromatic aldehydes under solvent-free conditions to afford the corresponding bis(indolyl)methanes in high to excellent yields.
Olyaei Abolfazl   +4 more
doaj   +1 more source

Monomer and polymer indole-derived systems having NLO properties for very high optical gain photorefractive materials. The role of the electrostatic interactions. [PDF]

open access: yes, 2009
Object of the present research is the study of some indole-based photorefractive (PR) materials. Novel indole-based NLO chromophores have been synthesized and their photoconductive (PC) and PR behaviour have been investigated when employed both alone (as
GRECO, FRANCESCO
core  

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Indole produced during dysbiosis mediates host–microorganism chemical communication

open access: yeseLife, 2023
An imbalance of the gut microbiota, termed dysbiosis, has a substantial impact on host physiology. However, the mechanism by which host deals with gut dysbiosis to maintain fitness remains largely unknown.
Rui-Qiu Yang   +7 more
doaj   +1 more source

CH activation and CH2 double activation of indolines: towards the synthesis of aspidospermidine and aspidofractinine [PDF]

open access: yes, 2009
This thesis is concerned with the total synthesis of the two Aspidosperma alkaloid natural products, aspidospermidine and aspidofractinine. The two targets have a common pentacyclic molecular framework unique to this class of indole alkaloids ...
Whiting, Sally
core  

Supplementary Fig. S2 from Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1) [PDF]

open access: yes, 2009
Supplementary Fig. S2 from Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin ...
Jinsong Liu (6516)   +6 more
core   +1 more source

Indole primes defence signalling and increases herbivore resistance in tea plants [PDF]

open access: yes, 2021
Upon herbivore attack, plants emit herbivore‐induced plant volatiles (HIPVs). HIPVs can prime defences and resistance of intact plants. However, how HIPVs are decoded and translated into functional defence responses is not well understood, especially in ...
Xiwang Li   +13 more
core   +1 more source

New‐Era Polymer Thermoelectrics: Material Innovations, Doping Frontiers, Decoupling Strategies, and Unconventional Applications

open access: yesAdvanced Materials, EarlyView.
The field of polymer thermoelectrics is entering a new era, featuring breakthroughs in addressing the conventional performance disparity between p‐type and n‐type polymers, pioneering doping frontiers, and sophisticated decoupling strategies. This review explores innovations in molecular design and superior stabilities, bridging the gap from ...
Suhao Wang
wiley   +1 more source

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