Results 71 to 80 of about 195,525 (279)

Novel approach to bis(indolyl)methanes using nickel nanoparticles as a reusable catalyst under solvent-free conditions [PDF]

open access: yesJournal of the Serbian Chemical Society, 2013
A nanosized Nickel as catalyst has been developed for the electrophilic substitution reactions of indole with variousaromatic aldehydes under solvent-free conditions to afford the corresponding bis(indolyl)methanes in high to excellent yields.
Olyaei Abolfazl   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Simple indole alkaloids and those with a non-rearranged monoterpenoid unit. [PDF]

open access: yes, 2014
Covering: 2010-2011. Previous review: Nat. Prod. Rep. 2010, 27, 1630-1680This review covers the literature on simple indole alkaloids and those with a non-rearranged monoterpenoid unit from the beginning of 2010 up to the end of 2011, which includes ...
9000318134967   +11 more
core  

Indole produced during dysbiosis mediates host–microorganism chemical communication

open access: yeseLife, 2023
An imbalance of the gut microbiota, termed dysbiosis, has a substantial impact on host physiology. However, the mechanism by which host deals with gut dysbiosis to maintain fitness remains largely unknown.
Rui-Qiu Yang   +7 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Indole-Fused Benzoxepine Synthesis via Visible-Light-Driven Aerobic Dehydrogenative [5 + 2] Annulation

open access: yes, 2023
A photocatalyzed oxidative dehydrogenative annulation between 2-(1H-indol-2-yl)phenols and alkenylphenols is presented. Various indole-fused benzoxepines can be obtained at room temperature using atom-efficient strategies. This method not only avoids the
Kui Dong (8747232)   +3 more
core   +1 more source

Acetoacetates Derived From Vegetable Oils: A Platform for Tailor‐Made Vinylogous Urethane Foams

open access: yesAdvanced Functional Materials, EarlyView.
A renewable vegetable oil is converted into acetoacetate‐functionalized precursors for the preparation of catalyst‐free vinylogous urethane foams. Room‐temperature foaming with n‐pentane generates lightweight cellular materials, while the choice of amine enables control over foam structure and mechanical properties.
Krzysztof Polaczek   +8 more
wiley   +1 more source

Structure–Activity Relationship Studies of Indolglyoxyl-Polyamine Conjugates as Antimicrobials and Antibiotic Potentiators

open access: yesPharmaceuticals, 2023
Antibiotic resistance is a growing global health threat, requiring urgent attention. One approach to overcome antibiotic resistance is to discover and develop new antibiotic enhancers, molecules that work with legacy antibiotics to enhance their efficacy
Melissa M. Cadelis   +6 more
doaj   +1 more source

Structure‐Property Relationships in Catecholamine Coatings for Broad Surface Functionalization

open access: yesAdvanced Functional Materials, EarlyView.
Inspired by mussel adhesive proteins (MAPs), six catecholamine molecules with different molecular structure were systematically characterized and compared based on their ability to form homogeneous, reactive coatings. Highlighting candidates capable of balancing coating properties of interest, their successful use as primer layers for organic and ...
Caroline F. Harms   +5 more
wiley   +1 more source

N,N',N"-Tris[(5-methoxy-1H-indol-3-yl)ethyl]benzene-1,3,5-tricarboxamide

open access: yesMolbank, 2015
The title indole-based compound that enforces tripodal topology and is potential applicable for the use as artificial receptor, was prepared by a simple reaction of 1,3,5-benzenetricarbonyl trichloride with 5-methoxytryptamine.
Ute Schmidt, Manuel Stapf, Monika Mazik
doaj   +1 more source

Home - About - Disclaimer - Privacy