Results 101 to 110 of about 140,654 (327)

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

A performance test for boar taint compounds in live boars

Animal, 2013
Genetically reducing boar taint using low-taint lines is considered the most sustainable and economic long-term alternative to surgical castration of male pigs.
C. Baes, S. Mattei, H. Luther, S. Ampuero, X. Sidler, G. Bee, P. Spring, A. Hofer   +7 more
doaj   +1 more source

Acute and Chronic Toxicity of Indole Alkaloids from Leaves of Alstonia scholaris (L.) R. Br. in Mice and Rats

Natural Products and Bioprospecting, 2020
Alstonia scholaris (L.) R. Br. (Apocynaceae) is an evergreen tree that has been used to treat lung diseases. In this study, the toxicity profile of indole alkaloids from leaves of A. scholaris was investigated.
Yun-Li Zhao, Min Su, Jian-Hua Shang, Xia Wang, Guy Sedar Singor Njateng, Guang-Lei Bao, Jia Ma, Qing-Di Sun, Fang Yuan, Jing-Kun Wang, Xiao-Dong Luo   +10 more
doaj   +1 more source

Effect of feeding fermentable fibrerich feedstuffs lupin and chicory prior to slaughter with special emphasis on the effect on chemical boar taint in organic entire male and female pigs and technological meat quality [PDF]

, 2007
Boar taint is an off-flavour of pork caused primarily by skatole and, androstenone. Pig off-odour and flavour mostly caused by higher skatole concentrations in backfat.
Hansen, Laurits Lydehøj, Hansen-Møller, Jens, Henckel, Poul, Jensen, Jens Askov, Syriopoulos, Kostas   +4 more
core  

Triplet Energy Transfer‐Driven Intermolecular [2+2] Photocycloaddition of Acyclic Imines and Indoles: Facile Access to Azetidine‐Fused Indolines

Advanced Science, EarlyView.
An intermolecular aza‐Paternò‐Büchi reaction of indoles and acyclic imines is enabled by visible‐light‐driven triplet energy transfer, providing azetidine‐fused indolines up to 93% yield for 30 examples and providing a novel protocol to access previously inaccessible scaffolds. ABSTRACT Currently, successful examples of the aza‐[2+2] photocycloaddition
Gang Yang, Zeng Han, Hong Zhang, Xiuling Cui   +3 more
wiley   +1 more source

Endophytic Bacteria in Highland and Its Ability To Enhance Plant Growth Environment [PDF]

Journal of Global Innovations in Agricultural Sciences
The objective of this study was to isolate and characterize endophytic bacteria from the rhizosphere of local highland North Luwu rice, which exhibits the ability to promote plant development and function as a biofertilizer.
Siti Maryam Yasin, Elkawakib Syam’un, Burhanuddin Rasyid   +2 more
doaj   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Triazolinediones as highly enabling synthetic tools [PDF]

, 2016
Triazolinediones (TADs) are unique reagents in organic synthesis that have also found wide applications in different research disciplines, in spite of their somewhat "exotic" reputation.
Billiet, Stijn, Chattopadhyay, Subrata, De Bruycker, Kevin, Du Prez, Filip, Houck, Hannes, Winne, Johan   +5 more
core   +1 more source

Multifunctional Nano Immunostimulant: Overcoming Immunosuppressive Microenvironment for Antitumor Immunotherapy

Advanced Science, EarlyView.
A multifunctional nano immunostimulant is first proposed for efficient tumor immunotherapy. The ER targeted ability, superior ROS production, efficient GSH consumption, coupled with the HIF suppression, jointly arouses ICD/ferroptosis pathways to realize efficient tumor immunotherapy.
Guanhong Guo, Wenda Zhong, Huishuang Zhao, Yueying An, Xinyu Dong, Zhengbo Li, Shuangfeng Qin, Guangzhao Xu, Xiangguo Yue, Xudong Wang, Wen Sun, Zhe‐Sheng Chen, Weiguo Song, Liuya Wei, Fahui Li   +14 more
wiley   +1 more source

ANTIFUNGAL ACTIVITY FROM ETHYLACETATE EXTRACT OF Plumeria alba AGAINST Candida albicans

Jurnal Natural, 2013
An investigation on the chemical constituents of plumeria alba has been studied. The compound was extracted from the bark using n-hexane and ethyl acetate as solvent, respectively. The crude was subjected to chromatographic techniques.
Murniana Murniana, Israhadi Israhadi, Khairan Khairan, Nurdin Saidi   +3 more
doaj   +2 more sources