Variation in hemolytic activity of Brachyspira hyodysenteriae strains from pigs [PDF]
, 2016 Brachyspira hyodysenteriae is the primary cause of swine dysentery, which is responsible for major economic losses to the pig industry worldwide. The hemolytic activity of 10 B.
Boyen, Filip +8 more
core +4 more sources
Molecules, 2016 The α-aminoamide family of sodium ion channel blockers have exhibited analgesic effects on neuropathic pain. Here, a series of novel α-aminoamides containing an indole ring were designed and synthesized.
Haotian Li +5 more
doaj +1 more source
Theoretical investigation and design of some indole derivatives as potent β-glucuronidase inhibitors
Bulletin of the National Research Centre, 2020 Background β-glucuronidase enzyme is mostly found in plants and animals. It plays a vital role in detoxification of reactive metabolites that are interrelated to several illnesses and the growth of colon cancer.
Muhammad Tukur Ibrahim +3 more
doaj +1 more source
Bacterial Indole acetic acid ( IAA ) production by using local media and test its efficiency on soyabean plant [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2012 This study was included isolation and identification of bacterial isolates for growth promoter production ( Indol Acetic Acid ) by application of local culture and evaluate its efficiency.
Jamal. S. Hommod +2 more
doaj +1 more source
Indole carboxamides inhibit bovine testes hyaluronidase at pH 7.0 and indole acetamides activate the enzyme at pH 3.5 by different mechanisms [PDF]
Journal of Enzyme Inhibition and Medicinal Chemistry, 2008 Hyaluronidases are enzymes controlling many crucial physiological processes. Imbalanced enzymatic activity is connected with severe diseases. Because there is limited availability of drugs modulating hyaluronidase activity, the search for hyaluronidase interacting compounds is getting more and more important. A series of fifteen indole carboxamides and
Andre, Kaessler +3 more
openaire +2 more sources
Acta Chimica Slovenica1H-indole-2,3-dione 3-[4-(4-sulfamoylphenyl)thiosemicarbazones] (6a-j) were evaluated against Para-influenza-3, Reovirus-1, Sindbis, Coxsackie B4 and Punto Toro viruses. New 1-methyl-1H-indole-2,3-dione 3-[4-(4-sulfamoylphenyl)thiosemicarbazones] (7a-c)
Füsun Göktaş +4 more
doaj +1 more source
A fluorometric method for the estimation of tryptophan [PDF]
, 1949 The various colorimetric methods now employed for the estimation of tryptophan are not specific for tryptophan but give colored products with many compounds containing the indole nucleus, including indole itself.
Gordon, Malcolm, Mitchell, Herschel K.
core
Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels [PDF]
, 2018 Drugs do not act solely by canonical ligand–receptor binding interactions. Amphiphilic drugs partition into membranes, thereby perturbing bulk lipid bilayer properties and possibly altering the function of membrane proteins.
Aldrich, Richard W. +12 more
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Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals
Advanced Functional Materials, EarlyView.This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee +4 more
wiley +1 more source
Results in ChemistryA prominent heterocyclic system found in medications and natural goods is indoles. Due to the significance of this important ring system, a fresh batch of unique indole derivatives was created using indole carbohydrazide.
Zainab H. Mahdi +4 more
doaj +1 more source