The Role of the Placental Enzyme Indoleamine 2,3-Dioxygenase in Normal and Abnormal Human Pregnancy. [PDF]
Kudo Y, Sugimoto J.
europepmc +1 more source
Discovery of Novel Imidazothiazole-Based Hydroxamic Acid Derivatives as Potent Indoleamine 2,3-Dioxygenase 1 and Histone Deacetylase 6 Dual Inhibitors. [PDF]
Zhang S +6 more
europepmc +1 more source
Prognostic and predictive value of IDO expression in metastatic melanoma treated with Ipilimumab. [PDF]
von Bubnoff D +12 more
europepmc +1 more source
IDO1 promotes Echinococcus multilocularis infection by regulating the formation of neutrophil extracellular traps. [PDF]
Zhang H +7 more
europepmc +1 more source
Tuberculosis and comorbid depression: Association with serum indoleamine 2,3-dioxygenase activity.
Rana P +5 more
europepmc +1 more source
The Tryptophan-Kynurenine pathway in people living with HIV: a systematic review. [PDF]
Sebigi TW +4 more
europepmc +1 more source
Impact of Indoleamine 2,3-Dioxygenase Enzyme Activity in Neuroendocrine Tumors.
Mancini C +12 more
europepmc +1 more source
Enzymatic Oxidation of Tryptophan and Its Analogues by Heme-Containing Dioxygenases [PDF]
Lubis, Ali B
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Indoleamine 2,3-dioxygenase 2 (IDO2) is a newly discovered target proposed to be a promising therapeutic modulator of various peripheral and central pathological states such as autoimmune disorders and immune escape diseases like cancer. The lack of potent hIDO2 inhibitors presents a high demand for discovering novel hIDO2 inhibition strategies to ex ...
Şüküroğlu, Murat, Qaoud, Mohammed
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Dendritic cell (DC)-based cancer vaccines are currently being evaluated as novel anti-tumor vaccination strategies, but in some cases, they are demonstrated to have poor clinical efficacies than anticipated. A potential reason is immune tolerance due to the immunosuppressive enzyme, indoleamine-pyrrole 2,3-dioxygenase (IDO).
Xueling, Ou +6 more
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