Results 121 to 130 of about 173,121 (147)
Zn<sup>64</sup> aspartate modulates inflammation, tryptophan metabolism, and pancreatic function in diet-induced obesity. [PDF]
Sci RepTemnik M +9 more
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Indoleamine 2,3-dioxygenase 1 inhibition reverses cancer-associated fibroblast-mediated immunosuppression in high-grade serous ovarian cancer. [PDF]
FEBS Open BioLee H, Ho JY, Hwang IS, Choi YJ.
europepmc +1 more source
Regulation of dendritic cell immune function and maturation by the recombinant antigen p53 of Trichinella spiralis. [PDF]
Parasit VectorsYuan X, Yang X, Han C.
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Palestinian Medical and Pharmaceutical Journal, 2023
Indoleamine 2,3-dioxygenase 2 (IDO2) is a newly discovered target proposed to be a promising therapeutic modulator of various peripheral and central pathological states such as autoimmune disorders and immune escape diseases like cancer. The lack of potent hIDO2 inhibitors presents a high demand for discovering novel hIDO2 inhibition strategies to ex ...
Şüküroğlu, Murat, Qaoud, Mohammed
openaire +2 more sources
Indoleamine 2,3-dioxygenase 2 (IDO2) is a newly discovered target proposed to be a promising therapeutic modulator of various peripheral and central pathological states such as autoimmune disorders and immune escape diseases like cancer. The lack of potent hIDO2 inhibitors presents a high demand for discovering novel hIDO2 inhibition strategies to ex ...
Şüküroğlu, Murat, Qaoud, Mohammed
openaire +2 more sources
Journal of Cancer Research and Clinical Oncology, 2007
Dendritic cell (DC)-based cancer vaccines are currently being evaluated as novel anti-tumor vaccination strategies, but in some cases, they are demonstrated to have poor clinical efficacies than anticipated. A potential reason is immune tolerance due to the immunosuppressive enzyme, indoleamine-pyrrole 2,3-dioxygenase (IDO).
Xueling Ou, Xinyao Wu, Shaohui Cai
exaly +3 more sources
Dendritic cell (DC)-based cancer vaccines are currently being evaluated as novel anti-tumor vaccination strategies, but in some cases, they are demonstrated to have poor clinical efficacies than anticipated. A potential reason is immune tolerance due to the immunosuppressive enzyme, indoleamine-pyrrole 2,3-dioxygenase (IDO).
Xueling Ou, Xinyao Wu, Shaohui Cai
exaly +3 more sources
Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta
Journal of Reproductive Immunology, 2004 Studies in mice have suggested that the placenta is protected from immune rejection by maternal T cells by means of localised indoleamine 2,3-dioxygenase dependent depletion of tryptophan.
Yoshiki Kudo, Koso Ohama, Osamu Takikawa
exaly +2 more sources
Indoleamine 2,3-dioxygenase or Indoleamine-pyrrole 2,3-dioxygenase (IDO or INDO EC 1.13.11.42)
2009exaly +2 more sources
Cancer Research, 2016
Abstract In recent years, understanding of tumor immunology has led to significant advances in cancer immunotherapy. New approaches include selective blockade of checkpoints, harnessing tumor infiltrating lymphocytes (TILs) and use of intratumoral oncolytic viruses.
Daqing Wang +5 more
openaire +1 more source
Abstract In recent years, understanding of tumor immunology has led to significant advances in cancer immunotherapy. New approaches include selective blockade of checkpoints, harnessing tumor infiltrating lymphocytes (TILs) and use of intratumoral oncolytic viruses.
Daqing Wang +5 more
openaire +1 more source