Results 51 to 60 of about 3,209 (136)

Extracellular vesicles originating from melanoma cells promote dysregulation in haematopoiesis as a component of cancer immunoediting

Journal of Extracellular Vesicles, Volume 13, Issue 7, July 2024.
Abstract Haematopoiesis dysregulation with the presence of immature myeloid and erythroid immunosuppressive cells are key characteristics of the immune escape phase of tumour development. Here, the role of in vitro generated B16F10 tumour cell‐derived extracellular vesicles (tEVs) as indirect cellular communicators, participating in tumour‐induced ...
Doste R. Mamand, Safa Bazaz, Dara K. Mohammad, Xiuming Liang, Svetlana Pavlova, Carsten Mim, Susanne Gabrielsson, Joel Z. Nordin, Oscar P. B. Wiklander, Manuchehr Abedi‐Valugerdi, Samir EL‐Andaloussi   +10 more
wiley   +1 more source

Immunomodulatory properties of induced pluripotent stem cell-derived mesenchymal cells [PDF]

, 2016
not availableJia Ng, Kim Hynes, Gregory White, Kisha Nandini Sivanathan, Kate Vandyke, Peter Mark Bartold and Stan ...
Bartold, P., Gronthos, S., Hynes, K., Ng, J., Sivanathan, K., Vandyke, K., White, G.   +6 more
core   +1 more source

Upregulated expression of indoleamine 2, 3-dioxygenase in CHO cells induces apoptosis of competent T cells and increases proportion of Treg cells [PDF]

, 2011
Introduction The inflammatory enzyme indoleamine 2, 3-dioxygenase (IDO) participates in immune tolerance and promotes immune escape of IDO+ tumors. A recent hypothesis suggested that IDO may contribute to the differentiation of new T regulatory cells ...
Li, Hui, Liu, Juntian, Ren, Xiubao, Sun, Jingyan, Wei, Feng, Yang, Lili, Yu, Jinpu, Yu, Wenwen   +7 more
core   +3 more sources

Ce6 nanoassemblies: Molecular mechanism and strategies for combinational anticancer therapy

Aggregate, Volume 5, Issue 1, February 2024.
The photosensitizer chlorin e6 (Ce6) emerges as a promising option for molecular self‐assembly owing to its planar conjugated structure and hydrophobicity. The resulting self‐assembled nanoparticles exhibit enhanced pharmacokinetic profile and excellent biocompatibility.
Yuwei Liu, Shuting Xu, Qingyang Lyu, Yi Huang, Weiping Wang   +4 more
wiley   +1 more source

Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes [PDF]

, 2009
Background Tumor-specific cytotoxic T cells and infiltrating lymphocytes are frequently found in tumor tissues in patients with nasopharyngeal carcinoma (NPC).
Cai, Shao-Hui, Du, Jun, He, Yun-Wen, Liu, Peng, Xie, Bai-Lu, Yi, Yan-Mei, Zhang, Ge   +6 more
core   +3 more sources

Exploring the serotonin‐probiotics‐gut health axis: A review of current evidence and potential mechanisms

Food Science &Nutrition, Volume 12, Issue 2, Page 694-706, February 2024.
Effects of serotonin‐5HT on central nervous system & GI tract functions. Abstract Modulatory effects of serotonin (5‐Hydroxytryptamine [5‐HT]) have been seen in hepatic, neurological/psychiatric, and gastrointestinal (GI) disorders. Probiotics are live microorganisms that confer health benefits to their host.
Noor Akram, Zargham Faisal, Rushba Irfan, Yasir Abbas Shah, Syeda Ayesha Batool, Toobaa Zahid, Aqsa Zulfiqar, Areeja Fatima, Qudsia Jahan, Hira Tariq, Farhan Saeed, Aftab Ahmed, Aasma Asghar, Huda Ateeq, Muhammad Afzaal, Mahbubur Rahman Khan   +15 more
wiley   +1 more source

Vaccine strategies to improve anti-cancer cellular immune responses [PDF]

, 2019
More than many other fields in medicine, cancer vaccine development has been plagued by a wide gap between the massive amounts of highly encouraging preclinical data on one hand, and the disappointing clinical results on the other.
Vermaelen, Karim
core   +2 more sources

Anti‐Inflammatory and Microbiota‐Regulating Property of Deficiency Tonic Medicines in Edible Traditional Chinese Medicine: A Promising Therapy for Depressive Disorder

Journal of Food Biochemistry, Volume 2024, Issue 1, 2024.
Depression has become the leading cause of disability worldwide. Conventional serotonergic antidepressants fail to meet anticipated outcomes and increase the risk of drug dependency and side effects. Consequently, the significance of diet and nutrition in the prevention and management of depression and anxiety has increasingly received attention.
Siyu Ren, Peilin Qin, Gang Wang, Jian Yang, Akhilesh K. Verma   +4 more
wiley   +1 more source

Expression analysis of novel striatal-enriched genes in Huntington disease [PDF]

, 2017
Selective degeneration of striatal neurons is a pathologic hallmark of Huntington disease (HD). The exact mechanism(s) behind this specific neurodegeneration is still unknown.
Becanovic, Kristina, Leavitt, Blair R., Luthi-Carter, Ruth, Mazarei, Gelareh, Neal, Scott J., Simpson, Elizabeth M.   +5 more
core  

Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]

, 2018
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D., Brennan, Benjamin, Elliott, Richard M., Feng, Junjie, Koudriakova, Elina, Kreher, Felix, Rezelj, Veronica V., Rice, Charles M., Rihn, Suzannah J., Shaw, Andrew E., Shi, Xiaohong, Slack, Gillian S., Tilston-Lunel, Natasha L., Turnbull, Matthew L., Wickenhagen, Arthur, Wilson, Sam J.   +15 more
core   +1 more source