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Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

open access: yesFood Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao   +8 more
wiley   +1 more source

Chemistry, Applications, and Synthesis Methods of Indole Derivatives: A Comprehensive Review. [PDF]

open access: yesChem Rec
Silva Moratório de Moraes R   +10 more
europepmc   +1 more source

Shape-Conserving Atom Replacements. [PDF]

open access: yesChem Rev
Puriņš M, Elgindy C, Levin MD.
europepmc   +1 more source
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When indolent follicular lymphoma is not indolent

Leukemia & Lymphoma, 2014
Histological transformation of follicular lymphoma (FL) to a more aggressive, high-grade lymphoma is typically viewed as a pivotal event that defines the transition from an indolent disease to one ...
Tiffany, Tang, Peter, Martin
openaire   +2 more sources

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