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Calcium crystal–induced inflammation

Current Opinion in Rheumatology, 2001
Recent studies have added to our knowledge regarding the mechanisms of calcium crystal deposition. Calcium pyrophosphate dihydrate (CPPD) crystal deposition is associated with elevated levels of PPi in joints. Cyclic compression of cartilage transiently elevated ATP levels in culture media. Extracellular ATP may be hydrolyzed by nucleoside triphosphate
P B, Halverson, B A, Derfus
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Virus-Induced Cholesterol Crystals

Science, 1973
One of the crystal types induced in cell cultures by a new feline herpesvirus was identified as cholesterol by crystal structure, polarized light microscopy, and mass spectroscopy.
C G, Fabricant, L, Krook, J H, Gillespie
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Tip Induced Crystallization Lithography

Journal of the American Chemical Society, 2014
We demonstrate a new technique for efficiently fabricating large-area organic crystal arrays on substrates using tip induced crystallization lithography (TICL). This technique depends on coating an amorphous organic thin film on a substrate and then inducing crystallization of the thin film using an atomic force microscope tip. After the noncrystalline
Xin, Zhang, Brandon L, Weeks
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Pathogenesis of crystal-induced inflammation

Current Rheumatology Reports, 2001
Crystals are an important cause of inflammatory rheumatic diseases and provide relatively simple paradigms for modelling inflammatory responses in general. Thus, in the case of gout, we know that hyperuricemia leads to precipitation of monosodium urate (MSU) crystals in joints, which are taken up by leukocytes, and then an acute attack of arthritis is ...
R C, Landis, D O, Haskard
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Vinblastine-Induced Crystals in Toxoplasma

The Journal of Parasitology, 1984
termined using Student's t-test. Ascaris suum larval extract damaged peritoneal leucocytes at a concentration range of 1 to 100 mg protein/1 x 106 cells (Table I). Leucocyte suspensions were assayed for lysophospholipase activity by a modification of the method of Ottolenghi (1964, J. Lipid Res. 5: 532537). Tubes containing 0.1 ml of each cell mixture,
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Modeling Flow-Induced Crystallization

2016
A numerical model is presented that describes all aspects of flow-induced crystallization of isotactic polypropylene at high shear rates and elevated pressures. It incorporates nonlinear viscoelasticity, including viscosity change as a result of formation of oriented fibrillar crystals (shish), compressibility, and nonisothermal process conditions ...
Roozemond, Peter C.   +2 more
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Crystallization induced by fungi and bacteria

Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials
Crystallization induced by lithobiont microbial communities (fungi, bacteria, lichens) has received great attention in science and beyond. The studies discussed here focus on the mechanisms and factors of microbial biomineralization. The multilevel modelling approach, which made it possible to solve this interdisciplinary problem, is highlighted.
Olga, Frank-Kamenetskaya, Dmitry, Vlasov
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Crystal-Induced Arthropathy

JAMA, 1979
CURRENTLY, there are two well-known articular disorders associated with abnormal accumulation of crystals within the joint. In one, gout, clinical abnormalities generally antedate roentgenographic findings by many years, and the roentgenograms serve primarily to record the extent of disease and its response to therapy; in the second, calcium ...
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Crystal-Induced Inflammation of the Joints

Annual Review of Medicine, 1970
Interest in the study of gouty inflammation was reawakened by the successful use of polarized light microscopy to identify sodium urate crystals in synovial fluid from gouty joints (1). The technique of crystal identification itself has been reviewed recently in considerable detail (2).
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Control of Crystal-Induced Arthropathies

Rheumatic Disease Clinics of North America, 1989
Present approaches to the treatment to crystal-induced arthropathies and indications for their use are reviewed. Successes and limitations of such therapy are discussed and potential new approaches to treatment are discussed. Treatment of gout hyperuricemia is generally effective if appropriately applied and is likely to be improved principally by ...
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