Results 131 to 140 of about 664,609 (313)

A map and a pipe : a new approach to characterizing erosion-corrosion regimes of Fe in three dimensions using CFD modelling

open access: yes, 2009
In studies of erosion-corrosion, much work has been carried out in recent years to identify regimes of behaviour. Such regimes describe the transition between the erosion and corrosion dominated mechanisms.
Stack, M.M.   +2 more
core  

Cellular defense against H2O2-induced apoptosis via MAP kinase–MKP-1 pathway

open access: yes, 2004
Mitogen-activated protein (MAP) kinase phosphatase-1 (MKP-1) is an oxidative stress-inducible gene. In this study. we investigated signaling pathways involved in oxidative stress-induced MKP-1 expression and its role in apoptosis of rat mesangial cells ...
Tsuneo Konta   +19 more
core   +1 more source

A Hofer-Type Norm of Hamiltonian Maps on Regular Poisson Manifold

open access: yesJournal of Applied Mathematics, 2014
We define a Hofer-type norm for the Hamiltonian map on regular Poisson manifold and prove that it is nondegenerate. We show that the L1,∞-norm and the L∞-norm coincide for the Hamiltonian map on closed regular Poisson manifold and give some sufficient ...
Dawei Sun, Zhenxing Zhang
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Erk5 Mediates TGFβ1-induced Loss of Phenotype and Function in Human Podocytes

open access: yes, 2014
Diabetic nephropathy is one of the most common causes of renal impairment. Podocytes are specialised cells integral to normal kidney physiology, however in diabetes injury occurs leading to compromised function which is a critical factor in the ...
Irbaz I. Badshah   +8 more
core   +1 more source

Induced and inducible mappings between hyperspaces

open access: yesPesquimat, 2019
In this paper we consider H(X) be a hyperspace of a continuum X. Let f : X → Y be a continuous function between continua, consider the induced function H(f) : H(X) → H(Y ) given by H(f)(A) = f(A), for all A ϵ H(X). On the other hand, if we have the continuous function H : H(X) → H(Y ) and there exists g : X → Y such that H = H(f), we say that H is ...
openaire   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

open access: yesFEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez   +2 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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