Results 141 to 150 of about 664,609 (313)

The involvement of reactive oxygen species (ROS) and p38 mitogen-activated protein (MAP) kinase in TRAIL/Apo2L-induced apoptosis

, 2002
To determine the apoptotic signaling pathway which tumor necrosis factor-related apoptosis-inducing ligand (TRAIL/Apo2L) induced, we investigated the contribution of reactive oxygen species (ROS), p38 mitogen-activated protein (MAP) kinase and caspases ...
Lee, Myoung-Woo, Lee, Hyun Jung, Young Geun Yang, Lee, Won Bok, Chae, Hee Sun, Jae-Hyung Bach, Park, Soon Cheol, Bach, Jae-Hyung, Myoung-Woo Lee, Kim, Sung Su, Hyun Jung Lee, Won Bok Lee, Yim, Soon Ock, Sung Su Kim, Soon Ock Yim, Kyung Yong Kim, Yang, Young Geun, Kim, Kyung Yong, Hee Sun Chae, Soon Cheol Park   +19 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Role of MAP kinases and their cross-talk in TGF-beta1-induced apoptosis in FaO rat hepatoma cell line.

, 2002
Transforming growth factor (TGF) beta1 is a potent inducer of apoptosis in the liver. During TGF-beta1-induced apoptosis, 3 mitogen-activated protein (MAP) kinases (extracellular signal-regulated kinase [ERK], c-Jun N-terminal kinase [JNK], and p38 ...
Kim, BC, Choi, KS, Park, HJ, Kim, SJ
core   +1 more source

Bodily maps of exercise-induced feelings

Scientific Reports
Physical exercise is a strong physiological and mechanical stimulus that elicits various bodily sensations. They shape the emotional experience and contribute to the psychological benefits of exercise. Despite the centrality of subjective sensations stemming from altering bodily states during physical exercise, there is a paucity of data on bodily ...
Tiina Saanijoki, Lauri Nummenmaa
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Cell cycle-dependent regulation of structure of endoplasmic reticulum and inositol 1,4,5-trisphosphate-induced Ca2+ release in mouse oocytes and embryos

, 2003
The organization of endoplasmic reticulum (ER) was examined in mouse eggs undergoing fertilization and in embryos during the first cell cycle. The ER in meiosis 11 (MII)-arrested mouse eggs is characterized by accumulations (clusters) that are restricted
Carroll, J, Marangos, P, FitzHarris, G
core  

Transitivity of the Induced Map C n (f )

, 2020
. A map f : X → X, where X is a continuum, is said to be transitive if for each pair U and V of nonempty open subsets of X, there exists k ∈ N such that f k (U ) ∩ V = ∅. In this paper, we show relationships between transitivity of f and its induced maps
Javier Camargo, Cristian García, Ártico Ramírez   +2 more
core  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Induced-Polarization Energy Map: A Helpful Tool for Predicting Geometric Features of Anion-pi Complexes

[eng] In this manuscript we propose the use of a new tool that we have found useful to predict the geometries of ion-ð complexes. This tool is entitled the Induced-Polarization Energy map (IPE map).
Costa Torres, Antonio, Ballester Balaguer, Pablo José, Escudero, Daniel, Deyà Serra, Pere Maria, Frontera Beccaria, Antonio, Quiñonero Santiago, David   +5 more
core   +1 more source

HMGB-1 - a novel mediator of inflammatory-induced renal epithelial mesenchymal transition

, 2010
Background: High mobility group box protein 1 (HMGB-1) is a chromatin binding protein that bends DNA thereby facilitating gene transcription. HMGB-1 has also been observed as an extracellular secreted protein in serum of patients with sepsis and has ...
Ryan, Michael P., Michael P. Ryan, Slattery, Craig, Tara McMorrow, Nolan, Stephen, Ronan Feighery, Craig Slattery, Feighery, Ronan, Stephen Nolan, Julie Lynch, Lynch, Julie, McMorrow, Tara   +11 more
core   +1 more source