Results 41 to 50 of about 664,609 (313)

Cerium oxide nanoparticles inhibit lipopolysaccharide induced MAP kinase/NF-kB mediated severe sepsis

open access: yesData in Brief, 2015
The life threatening disease of sepsis is associated with high mortality. Septic patient survivability with currently available treatments has failed to improve.
Vellaisamy Selvaraj   +11 more
doaj   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Systematic map of the literature on carbon lock-in induced by long-lived capital

open access: yesEnvironmental Research Letters, 2021
Long-lived capital-stocks (LLCS) such as infrastructure and buildings have significant and long-lasting implications for greenhouse gas emissions. They contribute to carbon lock-in and may hinder a rapid decarbonization of energy systems. Here we provide
Vivien Fisch-Romito   +4 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

Heat Shock Protein 70 Negatively Regulates TGF-β-Stimulated VEGF Synthesis via p38 MAP Kinase in Osteoblasts

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: We previously demonstrated that transforming growth factor-β (TGF-β) stimulates the synthesis of vascular endothelial growth factor (VEGF) through the activation of p38 mitogen-activated protein (MAP) kinase in osteoblast-like MC3T3-E1 ...
Go Sakai   +7 more
doaj   +1 more source

A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice

open access: yesJournal of Immunology Research, 2020
Multiepitope peptide vaccine has some advantages over traditional recombinant protein vaccine due to its easy and fast production and possible inclusion of multiple protective epitopes of pathogens.
Yuan Gu   +4 more
doaj   +1 more source

The transitivity of induced maps

open access: yesTopology and its Applications, 2009
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Acosta, Gerardo   +2 more
openaire   +1 more source

Mapping the parameters of prion-induced neuropathology [PDF]

open access: yesProceedings of the National Academy of Sciences, 2000
We present a theoretical framework that enables us to dissect out the parametric dependencies of the pathogenesis of prion diseases. We are able to determine the influence of both host-dependent factors (connectivity, cell density, protein synthesis rate, and cell death) and strain-dependent factors (cell tropism, virulence, and replication rate).
M P, Stumpf, D C, Krakauer
openaire   +2 more sources

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Induced MO-mappings

open access: yesTsukuba Journal of Mathematics, 1999
All spaces are metrizable. The authors study the general question how properties of induced hyperspace maps can be translated in terms of properties of the original map, and vica versa. A continuous function \(f: X\to Y\) is said to be an MO-mapping provided that it can be written in the form \(f= f_1\circ f_2\) such that \(f_1\) is open and \(f_2\) is
Charatonik, Janusz Jerzy   +1 more
openaire   +3 more sources

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