Results 61 to 70 of about 664,609 (313)

The percentage increase in mean arterial pressure (MAP) induced by phenylephrine in different groups of rats

open access: yes, 2011
Copyright information:Taken from "Glutamine induces heat-shock protein and protects against lipopolysaccharide-induced vascular hyporeactivity in rats"http://ccforum.com/content/11/2/R34Critical Care 2007;11(2):R34-R34.Published online 9 Mar 2007PMCID ...
Liang Jing (84326)   +2 more
core   +1 more source

Isopanduratin A Inhibits Tumor Necrosis Factor (TNF)-α-Induced Nuclear Factor κB Signaling Pathway by Promoting Extracellular Signal-Regulated Kinase-Dependent Ectodomain Shedding of TNF Receptor 1 in Human Lung Adenocarcinoma A549 Cells

open access: yesBioChem, 2021
Tumor necrosis factor α (TNF-α) induces the nuclear factor κB (NF-κB) signaling pathway via TNF receptor 1 (TNF-R1). We recently reported that isopanduratin A inhibited the TNF-α-induced NF-κB signaling pathway in human lung adenocarcinoma A549 cells. In
Chihiro Moriwaki   +8 more
doaj   +1 more source

Openness of induced mappings

open access: yesTopology and its Applications, 1999
The authors investigate, for a map \(f : X \to Y\) between continua, when the induced map \(C(f): C(X) \to C(Y)\) is open. If \(X\) is either hereditarily locally connected or a fan then \(C(f)\) is open only when \(f\) is a homeomorphism. If \(X\) and \(Y\) are nondegenerate continua and \(f: X \times Y \to X\) is the natural projection, then \(C(f)\)
Charatonik, Janusz J.   +2 more
openaire   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Dietary fatty acids modulate inflammatory cytokine production through activation of MAP kinases [PDF]

open access: yes, 2007
Polyunsaturated fatty acids (PUFA) have therapeutic effects in inflammatory diseases, however the specific mechanisms by which they exert these effects have not yet been defined.
Braddish, Della
core  

Construction of a comparative genetic map in faba bean (Vicia faba L.); conservation of genome structure with Lens culinaris

open access: yes, 2008
Background The development of genetic markers is complex and costly in species with little pre-existing genomic information. Faba bean possesses one of the largest and least studied genomes among cultivated crop plants and no gene-based genetic maps ...
Carmen M. Avila   +31 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

MAPK phosphatase-1 represents a novel antiinflammatory target of glucocorticoids in the human endothelium [PDF]

open access: yes, 2007
Glucocorticoids are well-established anti- inflammatory drugs thought to mainly act by inhibition of proinflammatory transcription factors like NF-κB.
Timm Schroeder   +20 more
core   +1 more source

Naringenin Protects against Acute Pancreatitis in Two Experimental Models in Mice by NLRP3 and Nrf2/HO-1 Pathways

open access: yesMediators of Inflammation, 2018
Background. Naringenin (Nar) is a type of flavonoid and has been shown to have anti-inflammatory and antioxidative properties. However, the effects of Nar on acute pancreatitis (AP) have not been well studied.
Yong Li   +9 more
doaj   +1 more source

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