Results 71 to 80 of about 664,609 (313)

Tiam1-Rac1 Axis Promotes Activation of p38 MAP Kinase in the Development of Diabetic Retinopathy: Evidence for a Requisite Role for Protein Palmitoylation

open access: yesCellular Physiology and Biochemistry, 2015
Background/Aims: Evidence in multiple tissues, including retina, suggests generation of reactive oxygen species (ROS) and the ensuing oxidative stress as triggers for mitochondrial defects and cell apoptosis.
Rajakrishnan Veluthakal   +4 more
doaj   +1 more source

On maps of Grothendieck groups induced by completion

open access: yesJournal of Algebra, 2002
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Kamoi, Yuji, Kurano, Kazuhiko
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Openness of the induced map Cn (f) [PDF]

open access: yes, 2009
Given a map between compact metric spaces f : X ! Y , it is possible to induce a map between the n{fold hyperspaces Cn(f) : Cn(X) ! Cn(Y ) for each positive integer n. Let A and B be classes of maps. A general problem is to nd the interrelations between
Camargo, Javier
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

BWMK1, a Novel MAP Kinase Induced by Fungal Infection and Mechanical Wounding in Rice

open access: yesMolecular Plant-Microbe Interactions, 1999
The activation of the mitogen-activated protein (MAP) kinases by different environmental stresses has been previously observed in several dicot plant species. Here, we report the isolation of a novel MAP kinase in rice that is induced during infection by
Chaozu He   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Summary Review of MAP-Induced TLR and MHC Responses.

open access: yes, 2012
Summary Review of MAP-Induced TLR and MHC Responses.
Sangeeta Khare (141487)   +11 more
core   +1 more source

(-)-Epigallocatechin Gallate Reduces Platelet-Derived Growth Factor-BB-Stimulated Interleukin-6 Synthesis in Osteoblasts: Suppression of SAPK/JNK

open access: yesMediators of Inflammation, 2008
We previously showed that the mitogen-activated protein (MAP) kinase superfamily, p44/p42 MAP kinase, p38 MAP kinase, and stress-activated protein kinase (SAPK)/c-Jun N-terminal (JNK), positively plays a part in the platelet-derived growth factor-BB ...
Shinji Takai   +8 more
doaj   +1 more source

Role of p38alpha/beta MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B

open access: yesToxins, 2016
Lethal Toxin from Clostridium sordellii (TcsL), which is casually involved in the toxic shock syndrome and in gas gangrene, enters its target cells by receptor-mediated endocytosis.
Ilona Schelle   +3 more
doaj   +1 more source

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