Results 81 to 90 of about 637,201 (266)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Quotient Structures of BCK/BCI-Algebras Induced by Quasi-Valuation Maps
Axioms, 2018 Relations between I-quasi-valuation maps and ideals in B C K / B C I -algebras are investigated. Using the notion of an I-quasi-valuation map of a B C K / B C I -algebra, the quasi-metric space is induced, and several properties are ...
Seok-Zun Song +2 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Velocity map imaging of femtosecond laser induced photoelectron emission from metal nanotips
New Journal of Physics, 2014 A novel application of velocity-map imaging (VMI) is demonstrated, whereby the momentum distribution of photoelectrons ejected from a tungsten nanoscale metal tip (< 50 nm radius) is recorded following illumination with an ultrafast laser pulse.
A R Bainbridge, W A Bryan
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Perturbation of EGF-induced MAP kinase activation by TGF-ß1
Brazilian Journal of Medical and Biological Research, 1999 TGF-ß1 regulates both cellular growth and phenotypic plasticity important for maintaining a growth advantage and increased invasiveness in progressively malignant cells.
C.E. Wenner, S. Yan
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Shrinkage mappings and their induced penalty functions [PDF]
2014 IEEE International Conference on Acoustics, Speech and Signal Processing (ICASSP), 2014 Many optimization problems that are designed to have sparse solutions employ the l 1 or l 0 penalty functions. Consequently, several algorithms for compressive sensing or sparse representations make use of soft or hard thresholding, both of which are examples of shrinkage mappings.
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Cardiovascular Effect of Dorsal Periaqueductal Gray During Lipopolysaccharide-induced Hypotension
Basic and Clinical Neuroscience, 2022 Introduction: The central mechanism related to the cardiovascular response to lipopolysaccharide (LPS)-induced hypotension is not entirely known, but it is suggested that numerous brain areas such as dorsal periaqueductal gray (dPAG) are involved in this
Iraj Mirzaii-Dizgah +3 more
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