Results 101 to 110 of about 637,201 (266)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

A Hofer-Type Norm of Hamiltonian Maps on Regular Poisson Manifold

open access: yesJournal of Applied Mathematics, 2014
We define a Hofer-type norm for the Hamiltonian map on regular Poisson manifold and prove that it is nondegenerate. We show that the L1,∞-norm and the L∞-norm coincide for the Hamiltonian map on closed regular Poisson manifold and give some sufficient ...
Dawei Sun, Zhenxing Zhang
doaj   +1 more source

Induced and inducible mappings between hyperspaces

open access: yesPesquimat, 2019
In this paper we consider H(X) be a hyperspace of a continuum X. Let f : X → Y be a continuous function between continua, consider the induced function H(f) : H(X) → H(Y ) given by H(f)(A) = f(A), for all A ϵ H(X). On the other hand, if we have the continuous function H : H(X) → H(Y ) and there exists g : X → Y such that H = H(f), we say that H is ...
openaire   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Bodily maps of exercise-induced feelings

open access: yesScientific Reports
Physical exercise is a strong physiological and mechanical stimulus that elicits various bodily sensations. They shape the emotional experience and contribute to the psychological benefits of exercise. Despite the centrality of subjective sensations stemming from altering bodily states during physical exercise, there is a paucity of data on bodily ...
Tiina Saanijoki, Lauri Nummenmaa
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

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