Results 61 to 70 of about 4,122,423 (255)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Assortative Matching and Reputation [PDF]

open access: yes
Consider Becker's classic 1963 matching model, with unobserved fixed types and stochastic publicly observed output. If types are complementary, then matching is assortative in the known Bayesian posteriors (the 'reputations').
Axel Anderson, Lones Smith
core  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Incomplete Information and Small Cores in Matching Markets [PDF]

open access: yes
We study Bayesian Nash equilibria of stable mechanisms in centralized matching markets under incomplete information. We show that truth-telling is a Bayesian Nash equilibrium of the revelation game induced by a common belief and a stable mechanism if and
Jordi Massó, Lars Ehlers
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Amended Draft Response Plan

open access: yes, 2014
August 27, 2014 To: Induced Seismicity Stakeholder Group From: Rex Buchanan, Interim Director, Kansas Geological Survey Mike Tate, Chief, Bureau of Water, Dept.
Kansas Induced Seismicity State Task Force.
core  

Robust matching and its optimum.

open access: yes, 2023
reservedCon la presente trattazione si ha innanzi tutto l’intento di esaminare il concetto di matching robusto, introdotto da Hassin e Rubinstein in [1] ed esplicabile con il seguente gioco di somma zero con strategia pura..
COBALCHIN, MARIAVITTORIA
core  

Stability and Nash implementation in matching markets with couples [PDF]

open access: yes, 2008
Haake C-J, Klaus B. Stability and Nash implementation in matching markets with couples. Working Papers. Institute of Mathematical Economics. Vol 399. Bielefeld: Universität Bielefeld; 2008.We consider two-sided matching markets with couples.
Klaus, B.E.   +5 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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