Results 291 to 300 of about 10,022,913 (342)

Specificity of spontaneous mutations induced in mutA mutator cells

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2004
Escherichia coli cells expressing the mutA allele of a glyV (glycine tRNA) gene express a strong mutator phenotype. The mutA allele differs from the wild type glyV gene by a base substitution in the anticodon such that the resulting tRNA misreads certain aspartate codons as glycine, resulting in random, low-level Asp-->Gly substitutions in proteins ...
Sergey, Balashov, M Zafri, Humayun
openaire   +2 more sources

Radiation-Induced Mutations

Nature, 1962
Radiation, Genes and Man By Prof. Bruce Wallace and Prof. Th. Dobzhansky. Pp. xii + 205. (London: Methuen and Co., Ltd., 1960.) 18s. net.
openaire   +1 more source

INDUCED MUTATIONS IN PLANT BREEDING

Canadian Journal of Plant Science, 1975
not available
openaire   +1 more source

Analysis of induced mutations in Aspergillus nidulans I. UV- and HNO2-induced mutations

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1966
Abstract A method is described that permits the selective detection of forward and back mutations for a single cistron in Aspergillus nidulans . The method also permits an easy phenotypic distinction among true back mutants and suppressor mutations. The rate of spontaneous, UV- and HNO 2 -induced retromutations has been studied in 15 UV- and 14 HNO
C, Calvori, G, Murpurgo
openaire   +2 more sources

Experimental work on induced mutations

Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1988
The detection of changes in mutation rate in human populations remains extremely difficult. Thus estimation of genetic hazards of mutagens to man depends on extrapolation from experimental systems. Germ cells of animals show complex variations in sensitivity to mutagenic effects. Some agents predominantly affect stem cells or other immature germ cells,
openaire   +2 more sources

Radiation-Induced Mutations in Mammals

Radiology, 1950
There are two particular questions about radiation-induced mutations in mammals which should be of interest to radiologists: (1) How likely are mutations to occur, as a function of dose? (2) How serious are their effects? Let us first remind ourselves of the main classes of mutations recognized by geneticists.
openaire   +2 more sources

Induced mutations in maize

Israel Journal of Plant Sciences, 2007
Maize is one of the most powerful genetic systems for studying plant biology, and an important model system for the grasses. Key to its utility is the wide range of mutations that have been and can be induced in its genome. Here we review the current uses of mutagens in maize, including the wide range of endogenous transposable elements, as well as ...
Rita-Ann Monde, Clifford F. Weil
openaire   +1 more source

Population genetics of induced mutations

Environmental and Molecular Mutagenesis, 1995
The contribution of induced mutations to the burden of genetic disease in the context of population genetics is considered. A clear distinction is made between the effects of genetic disease and mutational events. Much of the existing burden of genetic disease is a consequence of mutations that occurred in the past.
openaire   +2 more sources

Chemically induced mutations in mice

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1966
Abstract Using the specific locus method, the ability of the chemical triethylenemelamine to induce gene mutations in mouse spermatogonial cells was tested and confirmed.
openaire   +2 more sources

Radiation Induced Mutations

1999
Mutations constitute an important risk to human health. If induced in the germline they may be transmitted to the progeny causing hereditary diseases. Somatic mutations contribute to the induction of cancer. The basic mechanisms can be studied at the cellular level in tissue culture systems. On the other hand can mutations also be investigated in human
openaire   +1 more source