Results 291 to 300 of about 390,247 (379)

Enhanced Generation of Induced Pluripotent Stem Cells from a Subpopulation of Human Fibroblasts

, 2009
James Byrne, Ha Nam Nguyen, Renee A. Reijo Pera   +2 more
openalex   +2 more sources

Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells [PDF]

, 2010
Sarita Panula, José V. Medrano, Kehkooi Kee, Rosita Bergström, Ha Nam Nguyen, Blake Byers, Kitchener D. Wilson, Joseph C. Wu, Carlos Simón, Outi Hovatta, Renee A. Reijo Pera   +10 more
openalex   +1 more source

Autoantibody pathogenicity in a multifocal motor neuropathy induced pluripotent stem cell–derived model

Annals of Neurology, 2016
O. Harschnitz, Leonard H. van den Berg, L. Johansen, Marc D. Jansen, Sandra Kling, Renata Vieira de Sá, L. Vlam, W. van Rheenen, H. Karst, C. Wierenga, R. J. Pasterkamp, W. L. van der Pol   +11 more
semanticscholar   +1 more source

Pharmacological Inhibition of β Myosin II Disrupts Sarcomere Assembly in Human iPSC‐Derived Cardiac Myocytes

Cytoskeleton, EarlyView.
ABSTRACT Sarcomeres are the fundamental contractile units of striated muscle. The functional roles of the cardiac‐specific myosin heavy chains, MYH6 (α myosin II) and MYH7 (β myosin II) during sarcomere assembly remain controversial. To address this, we utilized a selective MYH7 inhibitor, mavacamten, in combination with siRNA‐mediated knockdown of ...
James B. Hayes, Dylan T. Burnette
wiley   +1 more source

Human induced pluripotent stem cell-derived myotubes to model inclusion body myositis. [PDF]

Acta Neuropathol Commun
Cantó-Santos J, Valls-Roca L, Tobías E, García-García FJ, Guitart-Mampel M, Andújar-Sánchez F, Vilaseca-Capel A, Esteve-Codina A, Martín-Mur B, Padrosa J, Peruga E, Madrigal I, Segalés P, García-Ruiz C, Fernández-Checa JC, Moreno-Lozano PJ, O'Callaghan AS, Sevilla A, Milisenda JC, Garrabou G.   +19 more
europepmc   +1 more source

Generation of mouse-induced pluripotent stem cells with plasmid vectors [PDF]

, 2010
Keisuke Okita, Hyenjong Hong, Kazutoshi Takahashi, Shinya Yamanaka   +3 more
openalex   +1 more source

NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming

Cell Reports, 2016
Kate E. Hawkins, S. Joy, J. Delhove, Vassilios Kotiadis, E. Fernandez, Lorna M. Fitzpatrick, J. Whiteford, P. J. King, J. Bolaños, M. Duchen, S. Waddington, T. McKay   +11 more
semanticscholar   +1 more source

Update on preclinical models of cancer therapy‐related cardiac dysfunction: Challenges and perspectives. A scientific statement of the Heart Failure Association (HFA) of the ESC, the ESC Council of Cardio‐Oncology, and the ESC Working Group on Cellular Biology of the Heart

European Journal of Heart Failure, EarlyView.
New anticancer therapies with potential cardiovascular side effects are continuously being introduced into clinical practice, with new and often unexpected toxicities becoming apparent only after clinical introduction. These unknown toxicities should be identified and understood beforehand to better prepare patients and physicians, enabling the ...
Alessandra Ghigo, Pietro Ameri, Aarti Asnani, Edoardo Bertero, Rudolf A. de Boer, Dimitrios Farmakis, Arantxa González, Stephane Heymans, Borja Ibáñez, Teresa López‐Fernández, Alexander R. Lyon, Piero Pollesello, Amina Rakisheva, Konstantinos Stellos, Katrin Streckfuss‐Bömeke, Carlo Gabriele Tocchetti, Thomas Thum, Peter van der Meer, Eva Van Rooij, Piotr Ponikowski, Marco Metra, Giuseppe Rosano, Sophie Van Linthout   +22 more
wiley   +1 more source

Protocol for immunofluorescence characterization of drusen in induced pluripotent stem cell-derived retinal pigment epithelium cultures. [PDF]

STAR Protoc
Dalvi S, Singh R.
europepmc   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source