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Generation of Induced Pluripotent Stem Cells in Rabbits
2014We describe a procedure for generating induced pluripotent stem cell lines in rabbits, using retroviral vectors expressing Oct4, Sox2, Klf4, and c-Myc of human origin to reprogram rabbit fibroblasts prepared from an ear skin biopsy. We also provide detailed procedures for characterizing the resulting iPSC lines, including the analysis of pluripotency ...
Marielle Afanassieff +5 more
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Battle for Pluripotency: Derivation of Induced Pluripotent Stem Cells
Recent Patents on Regenerative Medicine, 2011Since the first report on induced pluripotent stem (iPS) cells in 2006, iPS cells have attracted great public attention and research interest. Like embryonic stem (ES) cells, iPS cells are capable to self-renew infinitely, and maintain the developmental potential to differentiate into any types of cells in the body.
Lingyi Chen, Chunlin Mou
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Induced Pluripotent Stem Cells
The Egyptian Journal of Histology, 2011Shinya Yamanaka, Keisuke Okita
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Induced Pluripotent Stem Cells — A Cautionary Note
New England Journal of Medicine, 2011There are two sources of the human pluripotent stem cell — the differentiated somatic cell, such as a skin fibroblast, and the embryo. Recent studies suggest that an extra level of caution is warranted in using stem cells derived from somatic cells.
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Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
Science, 2007Junying Yu +11 more
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A safer stem cell: inducing pluripotency [PDF]
Nature Medicine, 2009 Derek van der Kooy, Laura Clarke
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Variation in the safety of induced pluripotent stem cell lines
Nature Biotechnology, 2009Kyoko Miura +13 more
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