Results 41 to 50 of about 216,890 (260)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

ANN-based prediction model for single-hole water inflow from piedmont to inland plain areas of Hebei Province, North China Plain

Journal of Groundwater Science and Engineering
This study, based on Artificial Neural Network (ANN) technology, develops a quantitative prediction model for the unit water flow rate of the Quaternary strata in the Shijiazhuang-Hebei Plain area.
Hong-wei Song, Fan Xia, Wei-qiang Wang, Ming-sen Shang, Jian-ye Gui   +4 more
doaj   +1 more source

Electrical Resistivity Tomography and Induced Polarization for Mapping the Subsurface of Alluvial Fans: A Case Study in Punata (Bolivia)

Geosciences, 2016
Conceptual models of aquifer systems can be refined and complemented with geophysical data, and they can assist in understanding hydrogeological properties such as groundwater storage capacity.
Andres Gonzales Amaya, Torleif Dahlin, Gerhard Barmen, Jan-Erik Rosberg   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The monitoring experiment of ZVI-AC material on nitrate pollution remediation effect by induced polarization method

地球与行星物理论评
Nitrate pollution has received high attention due to its characteristics such as universality and the high carcinogenicity rate of its reduction products.
Chen Chao, Jiaming Zhang, Xinmin Ma, Lili Guo, Shiliang Liu, Shupeng Li, Deqiang Mao   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

High resolution electromagnetic methods and low frequency dispersion of rock conductivity

Annals of Geophysics, 1999
The influence of frequency dispersion of conductivity (induced polarization) of rocks on the results of electromagnetic (EM) sounding was studied on the basis of calculation of electric field of vertical magnetic dipole above horizontally layered ...
V. V. Ageev, B. S. Svetov
doaj   +1 more source

Dynamically Induced Multiferroic Polarization

Physical Review Letters
We describe a mechanism by which both ferroelectric polarization and magnetization can be created in nonpolar, nonmagnetic materials. Using a combination of phenomenological modeling and first-principles calculations, we demonstrate that ferroelectric polarization, magnetization, or both simultaneously can be transiently induced by an ultrashort laser ...
Carolina Paiva, Michael Fechner, Dominik M. Juraschek   +2 more
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source