Results 51 to 60 of about 259,340 (309)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

The monitoring experiment of ZVI-AC material on nitrate pollution remediation effect by induced polarization method

地球与行星物理论评
Nitrate pollution has received high attention due to its characteristics such as universality and the high carcinogenicity rate of its reduction products.
Chen Chao, Jiaming Zhang, Xinmin Ma, Lili Guo, Shiliang Liu, Shupeng Li, Deqiang Mao   +6 more
doaj   +1 more source

Nonlinear Saturable and Polarization-induced Absorption of Rhenium Disulfide

, 2017
Monolayer of transition metal dichalcogenides (TMDs), with lamellar structure as that of graphene, has attracted significant attentions in optoelectronics and photonics.
Liu, Xueming, Cui, Yudong, Lu, Feifei
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

High resolution electromagnetic methods and low frequency dispersion of rock conductivity

Annals of Geophysics, 1999
The influence of frequency dispersion of conductivity (induced polarization) of rocks on the results of electromagnetic (EM) sounding was studied on the basis of calculation of electric field of vertical magnetic dipole above horizontally layered ...
V. V. Ageev, B. S. Svetov
doaj   +1 more source

Dynamics of microvortices induced by ion concentration polarization

, 2015
Image data belonging to the publication: Dynamics of microvortices induced by ion concentration polarization, Joeri C. de Valença, R. Martijn Wagterveld, Rob G. H.
Lammertink, R.G.H. (Rob), Tsai, P.A. (Peichun Amy), de Valença, J.C. (Joeri), Wagterveld, R.M. (Martijn)   +3 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Electrical resistivity and induced polarization in the investigation of acid drainage in decommissioning a mine

REM: International Engineering Journal
The opening and development of mines without previous planning can generate costly environmental liabilities that are difficult to recover. The Osamu Utsumi Mine was responsible for extracting uranium until 1995 in open pit mining operations. The sulfide
Beatriz Guzzo Duz, César Augusto Moreira, Marcos Eduardo Hartwig, Felipe Queiroz Miano, Lucas Moreira Furlan   +4 more
doaj   +1 more source