Results 111 to 120 of about 12,028,372 (332)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Application of Pullulan to Induce Disease Resistance Against Diaporthe nobilis in Postharvest Kiwifruit

Food Frontiers
Kiwifruit stands out as a globally favored fruit owing to its palatable flavor and nutritional benefits. However, it continues to ripen after harvest, and this trait makes it more susceptible to fungal infections. Diaporthe spp.
Shukun Yu, Huanhuan Li, Lihong Han, Junjie Wang, Xiaofeng Tang, Zhao‐Jun Wei, Yongsheng Liu, Min Miao   +7 more
doaj   +1 more source

Harnessing microbial consortia for induced systemic resistance and sustainable management of dry root rot in cluster bean under hot arid climatic conditions

Frontiers in Microbiology
Dry root rot, caused by Macrophomina phaseolina, severely threatens cluster bean production, necessitating sustainable management strategies. This study aimed to screen, characterize and evaluate microbial isolates with antagonistic potential against M ...
Devendra Singh, Aman Verma, Kuldeep Singh Jadon, Hans Raj Mahla, Rajesh Kumar Kakani   +4 more
doaj   +1 more source

Erwinia carotovora subsp. carotovora and Erwinia-Derived Elicitors HrpN and PehA Trigger Distinct but Interacting Defense Responses and Cell Death in Arabidopsis

Molecular Plant-Microbe Interactions, 2003
We have used an hrp-positive strain of the soft rot pathogen Erwinia carotovora subsp. carotovora to elucidate plant responses to this bacterial necrotroph.
Tarja Kariola, Tiina A. Palomäki, Günter Brader, E. Tapio Palva   +3 more
doaj   +1 more source

SGLT2 Inhibition by Empagliflozin Promotes Fat Utilization and Browning and Attenuates Inflammation and Insulin Resistance by Polarizing M2 Macrophages in Diet-induced Obese Mice

EBioMedicine, 2017
Sodium-glucose cotransporter (SGLT) 2 inhibitors increase urinary glucose excretion (UGE), leading to blood glucose reductions and weight loss. However, the impacts of SGLT2 inhibition on energy homeostasis and obesity-induced insulin resistance are less
Liang Xu, N. Nagata, M. Nagashimada, F. Zhuge, Yinhua Ni, Guanliang Chen, E. Mayoux, S. Kaneko, Tsuguhito Ota   +8 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Circular polarization dependent study of the microwave photoconductivity in a two-dimensional electron system

, 2005
The polarization dependence of the low field microwave photoconductivity and absorption of a two-dimensional electron system has been investigated in a quasi-optical setup in which linear and any circular polarization can be produced in-situ.
A. L. Zakharov, B. Gorshunov, C. Jiang, F. Kuchar, G. Kozlov, J. H. Smet, K. von Klitzing, K. West, L. Pfeiffer, M. Dressel, R. Meisels, S. I. Dorozhkin, V. Umansky, V. I. Ryzhii, V. I. Ryzhii   +14 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Waitea circinata: a novel biocontrol agent against Meloidogyne enterolobii on tomato plants

Journal of Nematology
Root-knot nematodes (RKN), particularly Meloidogyne enterolobii, pose a significant threat to agriculture, with current management heavily reliant on agrochemicals due to a scarcity of resistant crop varieties.
Alves Gianlucca de Urzêda, Felipe CG, Denner RF, Mara RR, Leila GA   +4 more
doaj   +1 more source

Endophytic fungus Beauveria bassiana induces antioxidant enzyme activities and enhances the growth of Rhizoctonia solani-infected potato plants

Вестник защиты растений
The physiological and biochemical changes in potato plants colonized by the endophytic form of the entomophatogenic fungus Beauveria bassiana (Ascomycota: Hypocreales) were analyzed under biotic stress caused by infection with the phytopathogen ...
О. Г. Томилова, Х. П. Толоконникова, М. В. Тюрин, Н. А. Крюкова   +3 more
doaj   +1 more source