Results 161 to 170 of about 2,833,000 (351)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Apple mold heart disease, primarily caused by Trichothecium roseum, is the most severe disease affecting stored apples. Developing biocontrol resources as an alternative to chemical pesticides is crucial for the advancement of green agriculture.
Xiuna Guo +4 more
doaj +1 more source
Supplementary Figure 1 from NF-κB2/p52 Induces Resistance to Enzalutamide in Prostate Cancer: Role of Androgen Receptor and Its Variants [PDF]
Nagalakshmi Nadiminty +6 more
openalex +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Reduction of Contact Resistance in Interconnections Formed by Laser-Induced CVD.
Mikio Hongo +3 more
openalex +2 more sources
Erratum to: Induced resistance in potato to Phytophthora infestans—effects of BABA in greenhouse and field tests with different potato varieties [PDF]
Erland Liljeroth +3 more
openalex +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Introduction. In the context of sustainable agricultural production, agroecology aims at optimizing the economic and environmental performances of beneficial ecosystem services in order to (i) increase the productivity and resilience of cultivated ...
Le Mire, G. +6 more
doaj

