Results 191 to 200 of about 12,028,372 (332)

Mechanisms of Tetramycin-Induced Resistance to Rice Blast Disease in Oryza sativa L. [PDF]

Int J Mol Sci
Jiang H, Zhao C, Li D, Sun K, Xu Y, Pang K, Yu X, Shentu X.   +7 more
europepmc   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Induced resistance: an enhancement of basal resistance?

, 2002
Upon primary pathogen attack, plants activate resistance mechanisms at the site of infection. Besides this so-called basal resistance, plants have also the ability to enhance their defensive capacity against future pathogen attack. There are at least two types of biologically induced resistance.
Vos, M. de, Robben, C., Pelt, J.A. van, Loon, L.C. van, Pieterse, C.M.J.   +4 more
openaire   +4 more sources

Chemically Induced Resistance to Pathogen Infection in Arabidopsis by Cytokinin (Trans-Zeatin) and an Aromatic Cytokinin Arabinoside. [PDF]

Mol Plant Pathol
Hönig M, Cortleven A, Petřík I, Simerský R, Bryksová M, Plíhal O, Schmülling T.   +6 more
europepmc   +1 more source

Induced plant resistance [PDF]

New Phytologist, 2001
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

How should APOBEC3-induced resistance mutations be considered in the management of antiretroviral therapy? [PDF]

J Antimicrob Chemother
Gilbert M, Ferré VM, Guilbaud R, Digumber M, Peytavin G, Damond F, Le Hingrat Q, Yazdanpanah Y, Descamps D, Charpentier C, Joly V, Ghosn J.   +11 more
europepmc   +1 more source

Analog of microwave-induced resistance oscillations induced in GaAs heterostructures by terahertz radiation

, 2016
T. Herrmann, I. Dmitriev, D. A. Kozlov, Markus P. Schneider, B. Jentzsch, Z. Kvon, P. Olbrich, V. Bel'kov, A. Bayer, D. Schuh, D. Bougeard, T. Kuczmik, M. Oltscher, D. Weiss, S. Ganichev   +14 more
semanticscholar   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Mutation-Induced Resistance of SARS-CoV-2 M^pro to WU-04 Revealed by Multi-Scale Modeling. [PDF]

Int J Mol Sci
Liu M, Zhao D, Duan H, Zhu J, Zheng L, Yuan N, Xia Y, Sang P, Yang L.   +8 more
europepmc   +1 more source