Results 211 to 220 of about 12,028,372 (332)

Mechanisms underlying the resistance to diet-induced obesity in germ-free mice

Proceedings of the National Academy of Sciences of the United States of America, 2007
F. Bäckhed, J. Manchester, C. Semenkovich, J. Gordon   +3 more
semanticscholar   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Special Issue: Advances in Plant Virus Diseases and Virus-Induced Resistance. [PDF]

Int J Mol Sci
Martínez-Gómez P.
europepmc   +1 more source

Polymorphism of virulence genes and biofilm associated with in vitro induced resistance to clarithromycin in Helicobacter pylori. [PDF]

Gut Pathog, 2023
Rosli NA, Al-Maleki AR, Loke MF, Chua EG, Alhoot MA, Vadivelu J.   +5 more
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

A statistical framework for detecting therapy-induced resistance from drug screens. [PDF]

NPJ Syst Biol Appl
Wu C, Gunnarsson EB, Foo J, Leder K.
europepmc   +1 more source

Diabetic cardiomyopathy: a hyperglycaemia- and insulin-resistance-induced heart disease

Diabetologia, 2017
Guanghong Jia, A. Whaley-Connell, J. Sowers   +2 more
semanticscholar   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Bactericidal activity and Inhibition of levofloxacin-induced resistance by antibacterial combination against hypervirulent Klebsiella pneumoniae. [PDF]

Ann Clin Microbiol Antimicrob
Aimaiti A, Xu Q, Ding L, Li Y, Li D, Suo J, Zhao X, Xu X, Wang M.   +8 more
europepmc   +1 more source

Induced resistance to Helicoverpa armigera through exogenous application of jasmonic acid and salicylic acid in groundnut, Arachis hypogaea.

Pest Management Science, 2015
A. War, M. G. Paulraj, S. Ignacimuthu, H. Sharma   +3 more
semanticscholar   +1 more source