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Regulation of the expression of inducible nitric oxide synthase
Nitric Oxide, 2010Nitric oxide (NO) generated by the inducible isoform of nitric oxide synthase (iNOS) is involved in complex immunomodulatory and antitumoral mechanisms and has been described to have multiple beneficial microbicidal, antiviral and antiparasital effects.
Andrea, Pautz +5 more
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Inflammation, immunoregulation, and inducible nitric oxide synthase
Journal of Leukocyte Biology, 1993Abstract Nitric oxide (NO), the molecule of the year 1992, is gaining recognition as an important biological mediator. Its multitude of physiologic and pathophysiologic functions result from both a wide distribution of synthesis and diverse mechanisms of action.
A K, Nussler, T R, Billiar
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Characterisation of bovine inducible nitric oxide synthase
Veterinary Immunology and Immunopathology, 2007Inducible nitric oxide (iNOS) is an enzyme that catalyzes the production of the reactive nitrogen intermediate nitric oxide (NO). NO is an important signalling molecule, released by numerous cells, that acts in many tissues to regulate a diverse range of physiological and biological processes, including neurotransmission, immune defence and the ...
Stephanie, Widdison +3 more
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Catalepsy induced by nitric oxide synthase inhibitors
General Pharmacology: The Vascular System, 19981. Previous study showed that N(G)-nitro-L-arginine (L-NOARG), an inhibitor of nitric bxide synthase, induces catalepsy in a dose-dependent manner in male albino-Swiss mice. 2. The objective of the present work was to further investigate this effect, extending it to other NOS inhibitors. 3.
E A, Del Bel +2 more
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Inducible Cyclooxygenase and Nitric Oxide Synthase
1995Publisher Summary Prostaglandin H synthase or cyclooxygenase (COX) and nitric oxide synthase (NOS) are distinct enzymes encoded by different genes. Their enzymatic mechanisms and kinetics as well as products are entirely different. However, they share certain biochemical and molecular characteristics.
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Inducible nitric oxide synthase expression in periodontitis
Journal of Periodontal Research, 2000Recently, nitric oxide (NO) has been shown to be vital in inflammatory processes. Nitric oxide synthase (NOS) exists in three different isoforms, two constitutively produced with physiological roles, and an inducible form, iNOS, which is involved in inflammation.
D F, Lappin +3 more
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Nitric oxide, inducible nitric oxide synthase and inflammation in veterinary medicine
Animal Health Research Reviews, 2002AbstractInflammation is a process consisting of a complex of cytological and chemical reactions which occur in and around affected blood vessels and adjacent tissues in response to an injury caused by a physical, chemical or biological insult. Much work has been performed in the past several years investigating inducible nitric oxide synthase (NOS, EC ...
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Inducible nitric oxide synthase in glial cells
Neuroscience Research, 1993Nitric oxide (NO), a free radical gas, has been suggested to mediate both synaptic plasticity and neuronal death. NO is generated by constitutive and inducible types of NO synthase (cNOS and iNOS, respectively). The neuronal cNOS was recently cloned, sequenced and characterized. In contrast, properties of iNOS in the brain are not fully understood.
Y, Nomura, Y, Kitamura
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Regulation of the expression of inducible nitric oxide synthase
European Journal of Pharmacology, 2004The role of nitric oxide (NO) generated by the inducible isoform of nitric oxide synthase (iNOS) is very complex. Induction of iNOS expression and hence NO production has been described to have beneficial antiviral, antiparasital, microbicidal, immunomodulatory, and antitumoral effects. However, induced at the wrong place or at the wrong time, iNOS has
Hartmut, Kleinert +3 more
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Regulation of the Expression of Inducible Nitric Oxide Synthase
Biological Chemistry, 2003Nitric oxide (NO), generated by the inducible isoform of nitric oxide synthase (iNOS), has been described to have beneficial microbicidal, antiviral, antiparasital, immunomodulatory, and antitumoral effects. However, aberrant iNOS induction at the wrong place or at the wrong time has detrimental consequences and seems to be involved in the ...
Hartmut, Kleinert +2 more
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