Results 171 to 180 of about 12,963 (191)
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Molecular Medicine Reports, 2017
Previous studies demonstrated that immune dysregulation is an important cause of hepatitis B virus (HBV)‑mediated liver damage. Co‑stimulators including programmed cell death protein 1 (PD‑1) and inducible T cell co‑stimulator (ICOS) are involved in the pathogenesis of HBV. In the present study, the serum levels of soluble (s)PD‑1 and sICOS in patients
Dongsheng, Wang +7 more
openaire +4 more sources
Previous studies demonstrated that immune dysregulation is an important cause of hepatitis B virus (HBV)‑mediated liver damage. Co‑stimulators including programmed cell death protein 1 (PD‑1) and inducible T cell co‑stimulator (ICOS) are involved in the pathogenesis of HBV. In the present study, the serum levels of soluble (s)PD‑1 and sICOS in patients
Dongsheng, Wang +7 more
openaire +4 more sources
Nature Medicine, 2015
T cell stimulation via glucocorticoid-induced tumor necrosis factor receptor (TNFR)-related protein (GITR) elicits antitumor activity in various tumor models; however, the underlying mechanism of action remains unclear. Here we demonstrate a crucial role for interleukin (IL)-9 in antitumor immunity generated by the GITR agonistic antibody DTA-1.
Il-Kyu, Kim +15 more
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T cell stimulation via glucocorticoid-induced tumor necrosis factor receptor (TNFR)-related protein (GITR) elicits antitumor activity in various tumor models; however, the underlying mechanism of action remains unclear. Here we demonstrate a crucial role for interleukin (IL)-9 in antitumor immunity generated by the GITR agonistic antibody DTA-1.
Il-Kyu, Kim +15 more
openaire +2 more sources
Inducible Co-Stimulator (ICOS) in transplantation: A review
Transplantation Reviews, 2022Mauro Sandrin +2 more
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Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2015
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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28
Nature, 1999Andreas Hutloff +2 more
exaly +2 more sources
Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA
Nature, 2007Christopher Goodnow +2 more
exaly

