Results 171 to 180 of about 12,963 (191)
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Aberrant production of soluble inducible T cell co-stimulator and soluble programmed cell death protein 1 in patients with chronic hepatitis B

Molecular Medicine Reports, 2017
Previous studies demonstrated that immune dysregulation is an important cause of hepatitis B virus (HBV)‑mediated liver damage. Co‑stimulators including programmed cell death protein 1 (PD‑1) and inducible T cell co‑stimulator (ICOS) are involved in the pathogenesis of HBV. In the present study, the serum levels of soluble (s)PD‑1 and sICOS in patients
Dongsheng, Wang   +7 more
openaire   +4 more sources

Glucocorticoid-induced tumor necrosis factor receptor–related protein co-stimulation facilitates tumor regression by inducing IL-9–producing helper T cells

Nature Medicine, 2015
T cell stimulation via glucocorticoid-induced tumor necrosis factor receptor (TNFR)-related protein (GITR) elicits antitumor activity in various tumor models; however, the underlying mechanism of action remains unclear. Here we demonstrate a crucial role for interleukin (IL)-9 in antitumor immunity generated by the GITR agonistic antibody DTA-1.
Il-Kyu, Kim   +15 more
openaire   +2 more sources

Inducible T‐cell co‐stimulator (ICOS) and ICOS ligand are novel players in the multiple‐myeloma microenvironment

British Journal of Haematology, 2022
Umberto Dianzani   +2 more
exaly  

Inducible Co-Stimulator (ICOS) in transplantation: A review

Transplantation Reviews, 2022
Mauro Sandrin   +2 more
exaly  

Roquin represses autoimmunity by limiting inducible T-cell co-stimulator messenger RNA

Nature, 2007
Christopher Goodnow   +2 more
exaly  

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