Results 61 to 70 of about 15,571 (268)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Induction and Co-induction in Sequent Calculus [PDF]

open access: yes, 2004
This is an extended and revised version of an extended abstract which appeared in the proceedings of TYPES ...
Alwen Tiu, Alberto Momigliano
openaire   +2 more sources

Fault-Tolerant Capability and Torque-Speed Measurements of Permanent Magnet Brushless AC Machines

open access: yesNigerian Journal of Technological Development, 2019
In this paper, the fault-tolerant capability in terms of inductance profile of a dual-stator permanent magnet brushless AC machine is presented. Similarly, its power-speed and torque-speed characteristics are also predicted.
C. C. Awah, O. I. Okoro
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Towards Determination of Inductive Resistances of Single-Core Cables with Voltage of up to 1 kV Insulated by Cross-Linked Polyethylene

open access: yesИзвестия высших учебных заведений и энергетических объединенний СНГ: Энергетика, 2018
To calculate short-circuit currents, voltage losses and reactive power in electrical networks, information on inductive resistances of cable lines is required.
V. N. Radkevich   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A computer vision approach with OpenCV and deep learning for determining inductance in planar coils

open access: yesVojnotehnički Glasnik
Introduction/purpose: In the realm of development and use of computer vision and AI methodologies, this research introduces a combination and advanced method using YOLOv9, a deep learning concept of whole image processing in one pass through a ...
Younes Benazzouz, Djilalia Guendouz
doaj   +1 more source

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