Results 61 to 70 of about 1,337 (291)

Modified double dumbbell-shaped split-ring resonator-based negative permittivity metamaterial for satellite communications with high effective medium ratio

open access: yesScientific Reports, 2021
Metamaterial with negative permittivity demonstrate excellent performance in cutting-edge technology. Thus, this study modified the double dumbbell-shaped split-ring resonator (MDD-SRR) based negative permittivity for satellite communications.
Md Bellal Hossain   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Novel grounded parallel inductance simulators realization using a minimum number of active and passive components [PDF]

open access: yes, 2010
In this paper novel lossless and lossy grounded parallel inductance simulators are reported. All grounded inductor simulator circuits employing only a single DXCCII and three passive components are proposed.
Abdullah Yeşil   +3 more
core   +1 more source

Analytical Equivalent Circuit Extraction of Foreign Metal Objects in WPT Systems

open access: yesIEEE Access
Wireless power transfer (WPT) technologies are rapidly attracting attention because of their wide application field. Among them, inductive power transfer (IPT) technology is most promising for daily usage in households.
Ryo Shirai   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Repeater insertion to minimise delay in coupled interconnects. [PDF]

open access: yes, 2001
Signalling over long interconnect is a dominant issue in electronic chip design in current technologies, with the device sizes getting smaller and smaller and the circuits becoming ever larger.
Tenhunen, Hannu   +2 more
core   +1 more source

XRL: An FMM-Accelerated SIE Simulator for Resistance and Inductance Extraction of Complicated 3-D Geometries [PDF]

open access: yes
A fast multipole method (FMM)-accelerated surface integral equation (SIE) simulator, called XRL, is proposed for broadband resistance/inductance (RL) extraction under the magneto-quasi-static assumption.
Wang, Mingyu   +4 more
core   +4 more sources

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

On dynamic delay and repeater insertion. [PDF]

open access: yes, 2002
In deep sub-micron technologies, as the wires are placed ever closer and signal rise and fall times go into the sub-nano second region, increased crosstalk has implications on the data throughput and on signal integrity. Depending on the data correlation
Tenhunen, Hannu   +4 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

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