Results 61 to 70 of about 262,428 (237)

Modified double dumbbell-shaped split-ring resonator-based negative permittivity metamaterial for satellite communications with high effective medium ratio

Scientific Reports, 2021
Metamaterial with negative permittivity demonstrate excellent performance in cutting-edge technology. Thus, this study modified the double dumbbell-shaped split-ring resonator (MDD-SRR) based negative permittivity for satellite communications.
Md Bellal Hossain, Mohammad Rashed Iqbal Faruque, Sikder Sunbeam Islam, Mohammad Tariqul Islam   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Analytical Equivalent Circuit Extraction of Foreign Metal Objects in WPT Systems

IEEE Access
Wireless power transfer (WPT) technologies are rapidly attracting attention because of their wide application field. Among them, inductive power transfer (IPT) technology is most promising for daily usage in households.
Ryo Shirai, Goro Nakao, Masanori Hashimoto   +2 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Grounded inductance simulator topologies realization with single current differencing current conveyor

, 2015
Actively simulated grounded inductors have been used in several applications ranging from filter to oscillator design as well as cancellation of parasitic inductances.
Kuntman, Ayten, Kacar, Firat, Kuntman, Hakan, Firat Kacar, Hakan Kuntman, Ayten Kuntman   +5 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Electronically tunable, active only floating inductance simulation

, 2003
In this paper a new floating inductance simulator employing only active elements is proposed. The proposed circuit uses one internally compensated operational amplifier and one dual output current controlled conveyor (CCCII).
Minaei, Shahram, Çiçekoğlu, Mehmet Oğuzhan, Türköz, Sait, Kuntman, Hakan   +3 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source