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VAD chemotherapy as remission induction for multiple myeloma [PDF]
British Journal of Cancer, 1995 A total of 142 patients with multiple myeloma received VAD as remission induction therapy. Seventy-five were previously untreated and 67 had relapsed (31) or refractory disease (36). Vincristine (total dose 1.6 mg) was infused with doxorubicin 36 mg m-2 by continuous ambulatory pump over 4 days. In addition, oral dexamethasone 40 mg day-1 was given for
L Fitzsimmons +7 more
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Induction of cancer cell stemness by chemotherapy [PDF]
Cell Cycle, 2012 Recent studies indicate that cancer stem cells (CSCs) exist in most hematological and solid tumors. CSCs are characterized by their ability to self-renew and their capacity to differentiate into the multitude of cells that comprise the tumor mass. Moreover, these cells have been shown to be intrinsically resistant to conventional anticancer therapies ...
Andrew C. Keates +6 more
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Survival After Induction Chemotherapy and Esophagectomy Is Not Improved by Adjuvant Chemotherapy [PDF]
The Annals of Thoracic Surgery, 2019 It remains unclear whether postoperative chemotherapy improves survival among patients with esophageal squamous cell carcinoma who have undergone preoperative chemotherapy and radical resection.Patients treated between January 2000 and December 2016 were reviewed.
Xiaozheng Kang +8 more
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Induction chemotherapy for locoregionally advanced nasopharyngeal carcinoma [PDF]
Chinese Journal of Cancer, 2016 The value of adding induction chemotherapy (IC) to concurrent chemoradiotherapy (CCRT) for the treatment of locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. In our recent article entitled "Induction chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in locoregionally advanced nasopharyngeal ...
Wen Fei Li, Ying Sun, Lei Chen, Jun Ma
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Chemotherapy: induction of stress responses
Endocrine-Related Cancer, 2006 Eukaryotic cells, from yeast to mammals, respond and adapt to environmental and microenvironmental stressors by evolutionary conserved multicomponent endogenous systems that utilise a network of signal transduction pathways to regulate the adaptive and protective phenotype. The balance between cell survival and cell death is decisive for sensitivity or
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Induction Chemotherapy for Locally Advanced Esophageal Cancer
Journal of Gastrointestinal Cancer, 2018 Concurrent chemoradiotherapy followed by surgery is the standard treatment for locally advanced esophageal cancer (EC), and the role of induction chemotherapy (IC) remains unclear. We aimed to study if the addition of IC to standard treatment increases the rate of pathologic complete response (pCR).We assembled a retrospective analysis of patients (pts)
Guilherme Harada +8 more
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Induction chemotherapy in sinonasal malignancies: A review of literature
Journal of Head and Neck Physicians and Surgeons, 2019 Sinonasal cancers form a distinct subset of head-and-neck tumors. They exhibit varied histologies with different clinical outcomes. These tumors are rare, and there exists no randomized trial identifying the ideal treatment for these patients. Induction chemotherapy (CT) has been tried with varying success for different purposes such as bioselection ...
Balasubramanian, Deepak +6 more
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Gemcitabine and Cisplatin Induction Chemotherapy in Nasopharyngeal Carcinoma
New England Journal of Medicine, 2019 Platinum-based concurrent chemoradiotherapy is the standard of care for patients with locoregionally advanced nasopharyngeal carcinoma. Additional gemcitabine and cisplatin induction chemotherapy has shown promising efficacy in phase 2 trials.In a parallel-group, multicenter, randomized, controlled, phase 3 trial, we compared gemcitabine and cisplatin ...
Yuan Zhang +46 more
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Neoadjuvant immunotherapy: is this the “new” induction chemotherapy? [PDF]
British Journal of Oral and Maxillofacial Surgery, 2019 Kanatas, AN, Doumas, S
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Responsiveness of Osteosarcoma to Induction Chemotherapy [PDF]
Otolaryngology–Head and Neck Surgery, 2010 David Wiesenfeld +4 more
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