Results 21 to 30 of about 1,332,541 (298)

Induction of cancer cell stemness by chemotherapy [PDF]

Cell Cycle, 2012
Recent studies indicate that cancer stem cells (CSCs) exist in most hematological and solid tumors. CSCs are characterized by their ability to self-renew and their capacity to differentiate into the multitude of cells that comprise the tumor mass. Moreover, these cells have been shown to be intrinsically resistant to conventional anticancer therapies ...
Xingwang, Hu, Laura, Ghisolfi, Andrew C, Keates, Jian, Zhang, Shuanglin, Xiang, Dong-ki, Lee, Chiang J, Li   +6 more
openaire   +2 more sources

Cyclophosphamide chemotherapy sensitizes tumor cells to TRAIL-dependent CD8 T cell-mediated immune attack resulting in suppression of tumor growth [PDF]

, 2009
Background: Anti-cancer chemotherapy can be simultaneously lymphodepleting and immunostimulatory. Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to ...
Amy Prosser, Robinson, B.W.S., Currie, A.J., Scalzo, A.A., Joanne Salmons, Robbert G van der Most, Mark J Smyth, Bruce W S Robinson, Salmons, J., Lake, R.A., Smyth Mark J., Andrew J Currie, Amanda L Cleaver, Prosser, Amy, van der Most, R.G., Degli-Esposti, M.A., Salmons, Joanne, Lake, Richard A., Prosser, A., Prosser Amy, Nowak, A.K., Currie, Andrew J., van der Most Robbert G., Smyth, M.J., Robinson Bruce W. S., Lake Richard A., Degli-Esposti, Mariapia A., Scalzo Anthony A., Currie Andrew J., Nowak, Anna K., Sathish Mahendran, Cleaver, Amanda L., Richard A Lake, Nowak Anna K., van der Most, Robbert G., Larma, I., Mahendran, S., Anna K Nowak, Degli-Esposti Mariapia A., Anthony A Scalzo, Cleaver, A.L., Robinson, Bruce W.S., Larma, Irma, Irma Larma, Cleaver Amanda L., Smyth, Mark J., Larma Irma, Mehendran, Sathish, Scalzo, Anthony A., Salmons Joanne, Mahendran Sathish, Mariapia A Degli-Esposti   +51 more
core   +2 more sources

Irreversible electroporation versus radiotherapy after induction chemotherapy on survival in patients with locally advanced pancreatic cancer: a propensity score analysis

BMC Cancer, 2019
Background Locally advanced pancreatic cancer (LAPC) represents more than one third of pancreatic cancers and owns poor survival after the standard chemotherapy. Irreversible electroporation (IRE) is a novel method and has been recently used in LAPC. The
Chaobin He, Jun Wang, Shuxin Sun, Yu Zhang, Xiaojun Lin, Xiangming Lao, Bokang Cui, Shengping Li   +7 more
doaj   +1 more source

Comparison of Induction Chemotherapy Plus Concurrent Chemoradiotherapy and Concurrent Chemoradiotherapy Alone in Locally Advanced Nasopharyngeal Carcinoma

Technology in Cancer Research & Treatment, 2021
Purpose: Induction chemotherapy plus concurrent chemoradiotherapy and concurrent chemoradiotherapy alone are both standard treatment regimens for managing locally advanced nasopharyngeal carcinoma.
Guoqiang Xu MD, Qiaoli Wang MD, Xingrao Wu MD, Chunyan Lv MD, Guilin Zeng MD, Zhihong Xue MD, Ruixue Cao MD, Nan Zhang BD, Wei Xiong PhD, Qin Huang MD   +9 more
doaj   +1 more source

Induction machine fault detection enhancement using a stator current high resolution spectrum [PDF]

, 2012
Fault detection in squirrel cage induction machines based on stator current spectrum has been widely investigated. Several high resolution spectral estimation techniques have been developed and used to detect induction machine abnormal operating ...
CHARPENTIER, Jean-Frederic, Vincent Choqueuse, EL BOUCHIKHI, El Houssin, BENBOUZID, Mohamed, Choqueuse, Vincent, V., Mohamed Benbouzid, El Houssin El Bouchikhi, Jean Frederic Charpentier, CHOQUEUSE, Vincent   +8 more
core   +1 more source

Predictive factors of toxicity of TPF induction chemotherapy for locally advanced head and neck cancers

BMC Cancer, 2021
Background The rate of toxic deaths related to induction chemotherapy in the treatment of locally advanced head and neck cancers is unacceptable and calls into question this therapeutic strategy, which is however highly effective in terms of rate and ...
Maureen Bernadach, Michel Lapeyre, Anne-Françoise Dillies, Jessica Miroir, Melanie Casile, Juliette Moreau, Ioana Molnar, Angeline Ginzac, Nathalie Pham-Dang, Nicolas Saroul, Xavier Durando, Julian Biau   +11 more
doaj   +1 more source

Use of in vitro human keratinocyte models to study the effect of cooling on chemotherapy drug-induced cytotoxicity [PDF]

, 2014
A highly distressing side-effect of cancer chemotherapy is chemotherapy-induced alopecia (CIA). Scalp cooling remains the only treatment for CIA, yet there is no experimental evidence to support the cytoprotective capacity of cooling. We have established
van den Hurk, Corina J., Komen, Manon M., Hussain, Omar, Dunnill, Christopher, Georgopoulos, Nikolaos T., Al-Tameemi, Wafaa, Collett, Andrew   +6 more
core   +1 more source

Prospective analysis of different combined regimens of stereotactic body radiation therapy and chemotherapy for locally advanced pancreatic cancer

Cancer Medicine, 2018
To identify impacts of different combined regimens of stereotactic body radiation therapy (SBRT) and chemotherapy on survival of patients with locally advanced pancreatic cancer (LAPC) and factors correlated with determinations of different combinations.
Xiaofei Zhu, Dongchen Shi, Fuqi Li, Xiaoping Ju, Yangsen Cao, Yuxin Shen, Fei Cao, Shuiwang Qing, Fang Fang, Zhen Jia, Huojun Zhang   +10 more
doaj   +1 more source

Survival After Induction Chemotherapy and Esophagectomy Is Not Improved by Adjuvant Chemotherapy [PDF]

The Annals of Thoracic Surgery, 2019
It remains unclear whether postoperative chemotherapy improves survival among patients with esophageal squamous cell carcinoma who have undergone preoperative chemotherapy and radical resection.Patients treated between January 2000 and December 2016 were reviewed.
Wanpu, Yan, Peiliang, Zhao, Hao, Fu, Yao, Lin, Zhongwu, Li, Liang, Dai, Yongbo, Yang, Xiaozheng, Kang, Ke-Neng, Chen   +8 more
openaire   +2 more sources

An operational definition of primary refractory acute myeloid leukemia allowing early identification of patients who may benefit from allogeneic stem cell transplantation

Haematologica, 2016
Up to 30% of adults with acute myeloid leukemia fail to achieve a complete remission after induction chemotherapy - termed primary refractory acute myeloid leukemia.
Paul Ferguson, Robert K. Hills, Angela Grech, Sophie Betteridge, Lars Kjeldsen, Michael Dennis, Paresh Vyas, Anthony H. Goldstone, Donald Milligan, Richard E. Clark, Nigel H. Russell, Charles Craddock   +11 more
doaj   +1 more source