Results 211 to 220 of about 262,962 (308)

Infections during AML induction chemotherapy in a contemporary cohort without fluoroquinolone prophylaxis. [PDF]

Infection
Ehrlich S, Eufinger J, Tahiri N, Jurinovic V, Mansournia S, Kunz WG, Jung J, Herold T, Subklewe M, Bücklein V, von Bergwelt-Baildon M, Spiekermann K.   +11 more
europepmc   +1 more source

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

Induction chemotherapy for acute leukemia

Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 1986
openaire   +4 more sources

Induction chemotherapy administration increases the risk of radiation pneumonitis in unresectable stage III NSCLC patients undergoing concurrent chemoradiotherapy with immunotherapy. [PDF]

Ther Adv Med Oncol
Li P, Qin Y, Liang X, Mo Y, Chen D.
europepmc   +1 more source

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Fluoroquinolone Prophylaxis Reduces Intensive Care Unit Admission and <i>Clostridioides difficile</i> Rates in Acute Myeloid Leukemia Induction Chemotherapy. [PDF]

EJHaem
Weeks CJ, Abbagoni S, Boghani F, Menon P, Gold M, Kannan C, Ismayilov O, Dalgetty M, Shah A, Delay L, Lim H, Mian M, Clarke A, Bryan L, Cortes J, Jillella A, Kota V.   +16 more
europepmc   +1 more source

Anti‐PD‐1 Nanobody‐Armored MSLN CAR‐T Therapy for Malignant Mesothelioma: Preclinical and Clinical Studies

Advanced Science, EarlyView.
A novel therapy using engineered immune cells (NAC‐T cells) showed promise for refractory malignant mesothelioma. Based on the encouraging preclinical data, the first‐in‐human trial is initiated, demonstrating tolerable safety and promising anti‐tumor activity (ORR 63.6%, DCR 100%, including one CR).
Yan Sun, Haochen Yang, Qing Xu, Xingya Li, Jinxing Lou, Jianchun Duan, Jiachen Xu, Zhuqing Liu, Yong Xia, Zhicai Lin, Linlin Li, Dan Sun, Jiaguo Li, Tao Liu, Jun Guo, Wenfeng Xu, Weimin Zhu, Yi Liu, Boyang Sun, Jia Zhong, Lijie Rong, Qijun Qian, Chenqi Xu, Jie Wang   +23 more
wiley   +1 more source

Longitudinal MRI Temporal Transformer Fusion Model for Predicting Induction Chemotherapy Efficacy in Locally Advanced Nasopharyngeal Carcinoma. [PDF]

Technol Cancer Res Treat
Han L, Chen X, Zhao Z, Liu Y, Yu D, Zhang H, Ge F.   +6 more
europepmc   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Spontaneous gaseous necrotizing myofasciitis in a patient with B-cell lymphoma status-post induction chemotherapy. [PDF]

J Surg Case Rep
Shields M, Remondelli MH, Wang AM, Barzanji NK, Wang J, Madha ES, Bradley MJ, Walker PF, Graybill JC.   +8 more
europepmc   +1 more source