Results 241 to 250 of about 418,262 (333)

VATS Pneumonectomy After Induction Chemotherapy

Annals of Clinical and Analytical Medicine, 2014
openaire   +1 more source

Doxorubicin‐Loaded Metal–Organic Framework for Ferroptosis‐Enhanced Chemotherapy Through Sustained Zn Release and Glutathione Peroxidase Downregulation

Advanced Healthcare Materials, EarlyView.
A robust zinc‐based metal–organic framework (ZnMOF) enables dual functions of doxorubicin delivery and sustained Zn2+ release to trigger ferroptosis‐enhnaced chemotherapy. DOX@ZnMOF effectively depletes intracellular glutathione, suppresses GPX4, and elevates reactive oxygen species, leading to efficient oxidative DNA damage and apoptosis.
Xin Ma, Chenghua Deng, Chaoyu Wang, Langston Tilman, Jinhong Li, Wenbin Lin   +5 more
wiley   +1 more source

Induction chemotherapy plus camrelizumab followed by concurrent chemoradiotherapy in unresectable locally advanced esophageal squamous cell carcinoma: a single-arm phase II trial. [PDF]

Nat Commun
Peng F, Wu J, Lian H, Wu S, Niu S, Xing X, Yang W, Song W, Li Y, Yu H, Feng ST, Wang X, Chen W, Ye W, Yu T, Liufu W, Cheng C, Bao Y.   +17 more
europepmc   +1 more source

Reduction of Proliferation and Induction of Apoptosis are Associated with Shrinkage of Head and Neck Squamous Cell Carcinoma due to Neoadjuvant Chemotherapy

, 2013
Shreya Sarkar, Guru Prasad Maiti, Jayesh Kumar Jha, Jaydip Biswas, Anup Roy, Susanta Roychoudhury, Tyson V. Sharp, Chinmay Kumar Panda   +7 more
openalex   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

A Nomogram Based on Tumor Response to Induction Chemotherapy and Plasma Epstein-Barr Virus DNA Level after Induction Chemotherapy to Explore Individualized Treatment of Patients with Locally Advanced Nasopharyngeal Carcinoma. [PDF]

J Inflamm Res
Liu F, Ma C, Chen M, Chen K, Zhu L, Li L, Zhu X, Qu S, Yan C.   +8 more
europepmc   +1 more source

Individualised cumulative cisplatin dose for locoregionally advanced nasopharyngeal carcinoma patients based on induction chemotherapy response and tumour volume

Jie‐Yi Lin, Zi-Jian Lu, Su‐Chen Li, Dong–Hua Luo, Ting Liu, Wan-Ru Zhang, Zhen‐Chong Yang, Hao‐Yuan Mo, Hai‐Qiang Mai, Sai-Lan Liu   +9 more
openalex   +1 more source

Photosensitizing Lipid Nanoparticles for Ferroptosis‐Enhanced Photodynamic Cancer Therapy via GPX4 Silencing

Advanced Healthcare Materials, EarlyView.
Photosensitizing lipid nanoparticles (PLNPs) are engineered by incorporating cholesterol–PEG–pheophorbide a into MC3‐based LNPs and encapsulating GPX4‐targeting siRNA. Upon light activation, PLNPs generate reactive oxygen species (ROS) while silencing GPX4 to induce ferroptosis.
Ga‐Hyun Bae, Seungyong Shin, Joo Dong Park, Eun‐Young Koh, Seunghyo Ko, Jieun Han, Chun Gown Park, Dong‐Hyun Kim, Kun Na, Wooram Park   +9 more
wiley   +1 more source

Treatment outcomes of squamous cell carcinoma of the external auditory canal and potential benefit of induction chemotherapy followed by chemoradiotherapy. [PDF]

Front Oncol
Mizunari Y, Nagaoka M, Takeshita N, Kanno K, Hirayama H, Akutsu T, Kessoku H, Ishida K, Yamamoto Y.   +8 more
europepmc   +1 more source

Association of Neutropenia with Oral Mucositis Development in Children with Acute Lymphoblastic Leukemia Undergoing Induction Chemotherapy [PDF]

Rafiqul Islam, Chowdhury Yakub Jamal, Waheeda Nargis, Maria J Mou, Tandra Chakma, M F Islam, Minha Islam   +6 more
openalex   +1 more source