Results 91 to 100 of about 284,586 (306)
Latent curing of epoxy-thiol thermosets [PDF]
, 2017 Epoxy-thiol curing is a click reaction which allows quantitative yield of the end products. The base-catalyzed reaction is rapid at low temperatures so it is most often desirable to harness reactivity by using latent catalysts.
Fernández Francos, Xavier +2 more
core +2 more sources
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
A 2-MHz 2-kW voltage-source inverter for low-temperature plasma generators: implementation of fast switching with a third-order resonant circuit [PDF]
, 1999 This paper presents a specially designed third-order resonant circuit intended to achieve fast switching operation for a voltage-source series-resonant inverter using four MOSFETs.
Akagi, Hirofumi, Fujita, Hideaki
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Induction plasma calcining of pigment particles for thermal control coatings Final report, 9 Feb. - 8 Aug. 1968 [PDF]
Induction plasma heating techniques used to calcinate pigment particles for thermal control ...
Bartlett, R. W.
core +1 more source
Thermal instability in ionized plasma [PDF]
, 2009 We study magnetothermal instability in the ionized plasmas including the effects of Ohmic, ambipolar and Hall diffusion. Magnetic field in the single fluid approximation does not allow transverse thermal condensations, however, non-ideal effects highly ...
A. Burkert +27 more
core +1 more source
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Transient heating of moving objects
Electrical engineering & Electromechanics, 2014 A mathematical model of transient and quasistatic heating of moving objects by various heat sources is considered. The mathematical formulation of the problem is described, examples of thermal calculation given.
E.I. Baida
doaj
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source