Results 91 to 100 of about 279,039 (336)

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

The research of heating efficiency of different induction heating systems

open access: yesMATEC Web of Conferences, 2017
Computer models of tape and coil inductors are described, and a comparison of the heating efficiency depending on various parameters is made. The developed computer model was made in the ELCUT 6.0.
Konesev Sergey   +3 more
doaj   +1 more source

Induction plasma calcining of pigment particles for thermal control coatings Final report, 9 Feb. - 8 Aug. 1968 [PDF]

open access: yes
Induction plasma heating techniques used to calcinate pigment particles for thermal control ...
Bartlett, R. W.
core   +1 more source

A 2-MHz 2-kW voltage-source inverter for low-temperature plasma generators: implementation of fast switching with a third-order resonant circuit [PDF]

open access: yes, 1999
This paper presents a specially designed third-order resonant circuit intended to achieve fast switching operation for a voltage-source series-resonant inverter using four MOSFETs.
Akagi, Hirofumi, Fujita, Hideaki
core   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Transient heating of moving objects

open access: yesElectrical engineering & Electromechanics, 2014
A mathematical model of transient and quasistatic heating of moving objects by various heat sources is considered. The mathematical formulation of the problem is described, examples of thermal calculation given.
E.I. Baida
doaj  

Deep Learning-Based Magnetic Coupling Detection for Advanced Induction Heating Appliances

open access: yesIEEE Access, 2019
Induction heating has become the reference technology for domestic heating applications due to its benefits in terms of performance, efficiency and safety, among others.
Oscar Lucia   +4 more
doaj   +1 more source

A benchmark problem of induction heating analysis

open access: yesInternational Journal of Applied Electromagnetics and Mechanics, 2017
In the paper, a benchmark in the area of induction heating is presented in order to test methods and codes of field analysis in a comparative way. In particular, the transient thermal analysis of a magnetic steel cylindrical billet is considered: the coupled-field problem is characterized by a twofold non linearity, i.e.
M. E. Mognaschi   +7 more
openaire   +5 more sources

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