Results 61 to 70 of about 7,098 (261)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Suppression of EMI radiation noise by inductor current recoil on boost PFC
The Journal of Engineering, 2018 As the development of switching power and power factor correction (PFC) technology in electronic devices, there is strong transient current rate and electromagnetic interference (EMI) noise caused by switching power supply MOSFET, IGBT, and other ...
Zhou Shen +6 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
High-Performance High-Power Inductor Design for High-Frequency Applications
IEEE Open Journal of Power ElectronicsMagnetic components significantly impact the performance and size of power electronic circuits. This is especially true at radio frequencies (RF) of many MHz and above.
Mansi V. Joisher +6 more
doaj +1 more source
Development of inductive-loaded ultra-wideband monopole antennas from stepped-impedance resonators
The Journal of Engineering, 2019 An ultra-wideband (UWB) printed monopole antenna is designed from stepped-impedance resonator (SIR) geometry. An inductor which is loaded in series between the radiating strips combines the multiple resonance bands of a two-strip stepped-impedance ...
Hefilia Asokan +2 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
EnergiesInductors are critical components in power electronic systems, yet their thermal behavior is often approximated using simplified lumped models that neglect internal gradients and transient spatial effects.
Francesco Montana, Daniele Scirè
doaj +1 more source