Results 51 to 60 of about 22,452 (291)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Negative Impedance Characteristics in Passive Inductors

open access: yes, 2022
Inductors, known as basic passive components, are the essential devices in power electronics converters. The high frequency characteristics, including parasitic capacitance, in inductors can introduce significant capacitive current to the system due to ...
Luan, Shaokang   +15 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Bubble inductors: Pneumatic tuning of a stretchable inductor [PDF]

open access: yesAIP Advances, 2017
From adaptive matching networks in power systems to channel selectable RF filters and circuitry, tunable inductors are fundamental components for circuits requiring reconfigurability. Here we demonstrate a new continuously tunable inductor based on physically stretching the inductor traces themselves.
Nathan Lazarus, Sarah S. Bedair
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Unified ZVS strategy for DAB with triple-phase-shift modulation in boost mode

open access: yesThe Journal of Engineering, 2019
In this study, the switching mode and working waveform of dual active bridge (DAB) converter under triple phase-shift modulation scheme is analysed, and an ALL-ZVS (zero voltage switching) control strategy of all devices for full-power range with voltage
Jian Qiu   +4 more
doaj   +1 more source

Saturation and thermal stability of power inductors

open access: yes, 2020
This paper discusses the effects of saturation of power inductors and their thermal stability. The investigation is focused on DC-DC switching regulators, with emphasis on fixed frequency controls. A small-change model is formulated for the assessment of
Nicola Femia   +2 more
core   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Fractional modelling and simulation for single-phase PWM rectifier

open access: yesThe Journal of Engineering, 2018
Modelling and analysis of single-phase PWM rectifier are usually based on integer order calculus theory, regardless of the fractional characteristics of inductors and capacitors, which will bring a deviation with the real system.
Pengfei Zhu   +4 more
doaj   +1 more source

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