Results 71 to 80 of about 22,452 (291)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Active damping method based self-adjust notch filter for current source converter
The Journal of Engineering, 2019 Inductor–capacitor (LC) filter in current source converter (CSC) exits resonance peak, which result in reducing control stability and amplifying harmonic component near resonance frequency.
Cheng Zhong, Qiang Chen, Zhou Jing
doaj +1 more source
Hysteretic Regulators with Partially-Saturated Inductors
, 2018 This paper investigates the performances of partially-saturated ferrite power inductors in DC-DC hysteretic regulators. Exploiting inductors saturation allows reducing the volume and weight of switch-mode power supplies, provided that inductors ripple ...
Nicola Femia, Giulia Di Capua
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Six-phase dual-interleaved buck-boost converter for high power-density automotive applications
The Journal of Engineering, 2019 This study presents a 30 kW, six-phase dual-interleaved buck-boost converter which uses an interphase transformer together with six buck-boost switching arms hard switched at 75 kHz for electric/hybrid vehicle applications.
P. E. Velázquez-Elizondo +5 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
EnergiesInductors are critical components in power electronic systems, yet their thermal behavior is often approximated using simplified lumped models that neglect internal gradients and transient spatial effects.
Francesco Montana, Daniele Scirè
doaj +1 more source
Benefits of the CI-CCS converter
The Journal of Engineering, 2019 An enhanced DC–DC converter is proposed in this paper, based on the combination of the Cuk converter and single-ended primary-inductor converter (SEPIC).
Kumaran S. Nathan +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
High-Performance High-Power Inductor Design for High-Frequency Applications
IEEE Open Journal of Power ElectronicsMagnetic components significantly impact the performance and size of power electronic circuits. This is especially true at radio frequencies (RF) of many MHz and above.
Mansi V. Joisher +6 more
doaj +1 more source