Results 131 to 140 of about 10,873,447 (395)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Heavy Metal Accumulation, Tissue Injury, Oxidative Stress, and Inflammation in Dromedary Camels Living near Petroleum Industry Sites in Saudi Arabia [PDF]
, 2022 Jamaan S. Ajarem +5 more
openalex +1 more source
Leading Lady: Sallie Mae and the Origins of Today's Student Loan Controversy [PDF]
, 2007 Over the past 40 years, the student loan industry has evolved from a relatively small, government-sponsored program into an $85 billion a year industry with thousands of lenders and industry-related companies.
Erin Dillon
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Water scarcity can be a critical limitation for the poultry industry [PDF]
, 2023 Mohamed I. El Sabry +4 more
openalex +1 more source
Australian Organic Market Report 2008 [PDF]
, 2008 Being four years since the publication of a similar research document, the Australian Organic Market Report (AOMR) 2008 is a landmark report for the organic industry.
Henryks, J. +3 more
core
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
Companies profitability under economic instability: evidence from the manufacturing industry in Russia [PDF]
, 2020 Vladislav Spitsin +3 more
openalex +1 more source
Industry expertise on audit committee and audit report timeliness [PDF]
, 2021 Nahla Abdulrahman Mohammed Raweh +3 more
openalex +1 more source
How Community Institutions Create Economic Advantage: Jewish Diamond Merchants in New York [PDF]
, 2006 This paper argues that Jewish merchants have historically dominated the diamond industry because of their ability to reliably implement diamond credit sales.
Richman, Barak D.
core +1 more source