Results 131 to 140 of about 10,424,348 (384)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Industry-driven innovative system development for the construction industry: The DIVERCITY project [PDF]
, 2004 Collaborative working has become possible using the innovative integrated systems in construction as many activities are performed globally with stakeholders situated in various locations.
Aouad, GF, Arayici, Y
core
Industry 4.0: state of the art and future trends
International Journal of Production Research, 2018 Lida Xu, E. Xu, L. Li
semanticscholar +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
A geographical study of the New Zealand textile manufacturing industry, with particular reference to the Wellington region [PDF]
, 1975 This thesis is a study of the New Zealand textile manufacturing industry and its components. It investigates the nature of location patterns, the changes within the components of the industry and the changes in industrial organisation which have occurred
Vickery, Evan Wakefield
core
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Disability Employment in the Hospitality Industry: Human Resources Considerations [PDF]
, 2012 [Excerpt] The characteristics of the hospitality industry are extremely dynamic and differ from other industries. In the United States and many other parts of the world, the predominant industry is transitioning from manufacturing to service.
Donnelly, Kelly, Joseph, Jeffrey
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Jurnal Ekonomi & Studi Pembangunan, 2010 Economic development has two goals, i.e. increasing income per capita and economic structural changes. In general, economic structural changes can be happen with changing of role or changing of contribution per sector.
hudiyanto hudiyanto
doaj
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source