Results 111 to 120 of about 4,113,041 (291)

Buffalo news : official newsletter of the Australian Buffalo Industry Council

open access: yes, 2003
This publication contains may contain links to external sites. These external sites may no longer be active.Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).Official newsletter of the Australian Buffalo ...
Australian Buffalo Industry Council
core   +2 more sources

Digital transformation of industrial business models: conceptual approaches and scenarios

open access: yesπ-Economy
Under the influence of the deepening digitalization of the economy and society, the practice of digital transformation of business models in industry is expanding, aimed at creating new technological, economic and market competitive advantages for ...
Krakovskaia Irina
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Paysages et labels : une communication autour de l’ancrage territorial renouvelé de l’industrie textile

open access: yesBulletin de l’Association de Géographes Français
The textile industry has helped to build industrial regions in France. After a period of crisis in the sector since the 1960s, the manufacturers who have continued in business have positioned themselves in niche markets (luxury, technical) and have ...
Mathieu Lembezat
doaj   +1 more source

Industrializing Biocatalysis

open access: yesCHIMIA
Biocatalysis leverages enzymes, nature’s catalysts, to enhance essential steps in chemical synthesis, thereby promoting more sustainable and efficient processes. Enzymes, macromolecular proteins, catalyze reactions with precision and efficiency in all living organisms.
Katrin, Hecht, Rebecca, Buller
openaire   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Buffalo news : official newsletter of the Australian Buffalo Industry Council

open access: yes, 2007
This publication contains may contain links to external sites. These external sites may no longer be active.Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).Official newsletter of the Australian Buffalo ...
Australian Buffalo Industry Council
core   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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