Results 91 to 100 of about 7,288,428 (297)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
A geographical study of the New Zealand textile manufacturing industry, with particular reference to the Wellington region [PDF]
, 1975 This thesis is a study of the New Zealand textile manufacturing industry and its components. It investigates the nature of location patterns, the changes within the components of the industry and the changes in industrial organisation which have occurred
Vickery, Evan Wakefield
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Telemarketing: Five Industry Centers [PDF]
, 2006 [Excerpt] In March 2006, the 4,789 business establishments classified as telemarketing bureaus (NAICS 561422) employed 337,662 workers. Weekly wages in the industry averaged $527 and workers’ average annual pay was $24,966.
Bureau of Labor Statistics
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
African vaccine manufacturing – The ecosystem and the Initiative
Journal of Public Health in AfricaN ...
Tolu Disu +4 more
doaj +1 more source
The Economic impact of Florida's recreational boating industry in 1985 [PDF]
, 1987 The recreational boating industry is an important component of Florida's economy. Previous Florida Sea Grant College supported research has documented this economic importance to the state's economy in 1980 (see Milon and Riddle, 1983, and Milon et al ...
Adams, Charles M., Minton, J. Walter
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
AFES Miscellaneous Publication 2013-03 [PDF]
, 2013 Tracking the growth and development of a new industry is critical to the assessment of its success. Growers, industry support groups, government leaders, educational and research organizations and more use basic statistics on crop production, markets,
Buchholz, Kathleen +1 more
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