Results 91 to 100 of about 3,101,699 (290)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
2nd Industry Contact Forum ; Thursday, June 27th, 2019: Program [PDF]
, 2019 At the 2nd Industry Contact Forum, doctoral researchers presented selected projects, and industrial partners and other organisations had the opportunity to present career paths in the Life ...
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Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The Internationalization of Industry Supply Chains and the Location of Innovation Activities [PDF]
, 2007 Current policy discussions on offshoring mostly focus on its impact on lower skilled manufacturing and services jobs, assuming that higher-value-added jobs and, especially, the location of innovation activities are not affected by offshoring.
Veloso, Francisco +2 more
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THE WORKFORCE OF HERZEGOVINA AND ITS INCLUSION IN THE PROCESS OF CROATIAN NATIONAL INTEGRATION [PDF]
Hum, 2013 With the arrival of Austrian-Hungarian monarchy in Bosnia and Herzegovina, transportation infrastructure and communications between settlements started to flourish.
Tihomir Zovko
doaj
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Buffalo news : official newsletter of the Australian Buffalo Industry Council [PDF]
, 2005 This publication contains may contain links to external sites.
Australian Buffalo Industry Council
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Return to R&D Investment and Spillovers in the Chinese Semiconductor Industry: A Tale of Two Segments [PDF]
, 2008 This study asks how a firm’s market orientation influences its returns to R&D investment and its capability to benefit from external technology opportunities brought about by the globalization of manufacturing and innovation activities. We use a panel of
Chesbrough, Henry +3 more
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