Results 71 to 80 of about 7,288,428 (297)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Designing a Model for Predicting Valuation of Block Trade Transactions with a Focus on GRU Artificial Neural Network in the Industry [PDF]
راهبرد مدیریت مالیPredicting the valuation of blockTrade transaction allows the market to evaluate control over companies in an efficient manner.In this research, by measuring the indicators affecting block transactions in three active industries in Tehran Stock Exchange ...
Adeleh Bahreini +2 more
doaj +1 more source
Dynamic modelling of a three-sector transitional economy [PDF]
, 2001 Rural industry provides inputs and markets for agriculture, which in turn provides inputs and markets for rural industry. As the mutually supportive linkages between rural industry and agriculture develop, the size of both sectors increases.
Harland, Derek, Lim, Steven
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
TECNOLOGIA DA INFORMAÇÃO E PRODUTIVIDADE NA INDÚSTRIA BRASILEIRA
RAE: Revista de Administração de Empresas, 2009 The article seeks to quantify the impact of information technology solutions on workers' productivity in the Brazilian processing industry. This study was based on a sample of 26,776 companies. This data was obtained from the Annual Industrial Study (PIA)
Jano Moreira de Souza +5 more
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Nursing OpenAim To explore how postgraduate leadership education is translated into practice and how leadership practices and behaviours are sustained following completion of a leadership program.
Rebekkah Middleton +4 more
doaj +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Sürtünme Karıştırma Nokta Kaynak Yönteminin Otomotiv Sektöründeki Yeri
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015 Bu çalışmada, sürtünme karıştırma nokta kaynak (SKNK) yönteminin otomotiv sektöründeki yeri incelenmiştir. SKNK, sürtünme karıştırma kaynağı (SKK) yönteminden türetilmiş ve otomotiv sektöründe oldukça dikkat çeken yeni bir kaynak yöntemidir.
Şenol MERT, Sevda MERT
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