Results 61 to 70 of about 4,259,857 (252)
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Buffalo news : official newsletter of the Australian Buffalo Industry Council
This publication contains may contain links to external sites. These external sites may no longer be active.Made available by the Northern Territory Library via the Publications (Legal Deposit) Act 2004 (NT).Official newsletter of the Australian Buffalo ...
Australian Buffalo Industry Council
core +2 more sources
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
TECNOLOGIA DA INFORMAÇÃO E PRODUTIVIDADE NA INDÚSTRIA BRASILEIRA
The article seeks to quantify the impact of information technology solutions on workers' productivity in the Brazilian processing industry. This study was based on a sample of 26,776 companies. This data was obtained from the Annual Industrial Study (PIA)
Jano Moreira de Souza +5 more
doaj
Aim To explore how postgraduate leadership education is translated into practice and how leadership practices and behaviours are sustained following completion of a leadership program.
Rebekkah Middleton +4 more
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Sürtünme Karıştırma Nokta Kaynak Yönteminin Otomotiv Sektöründeki Yeri
Bu çalışmada, sürtünme karıştırma nokta kaynak (SKNK) yönteminin otomotiv sektöründeki yeri incelenmiştir. SKNK, sürtünme karıştırma kaynağı (SKK) yönteminden türetilmiş ve otomotiv sektöründe oldukça dikkat çeken yeni bir kaynak yöntemidir.
Şenol MERT, Sevda MERT
doaj

