Results 81 to 90 of about 3,927,548 (340)
Sürtünme Karıştırma Nokta Kaynak Yönteminin Otomotiv Sektöründeki Yeri
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015 Bu çalışmada, sürtünme karıştırma nokta kaynak (SKNK) yönteminin otomotiv sektöründeki yeri incelenmiştir. SKNK, sürtünme karıştırma kaynağı (SKK) yönteminden türetilmiş ve otomotiv sektöründe oldukça dikkat çeken yeni bir kaynak yöntemidir.
Şenol MERT, Sevda MERT
doaj
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
, 1970 23 pages; available for download at the link below.In order to promote an orderly growth of ocean-related industry [in Texas] and, at the same time, insure proper management of the natural environment, it appears necessary that within the framework of ...
Industry Advisory Group
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
2nd Industry Contact Forum ; Thursday, June 27th, 2019: Program [PDF]
, 2019 At the 2nd Industry Contact Forum, doctoral researchers presented selected projects, and industrial partners and other organisations had the opportunity to present career paths in the Life ...
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
The Internationalization of Industry Supply Chains and the Location of Innovation Activities [PDF]
, 2007 Current policy discussions on offshoring mostly focus on its impact on lower skilled manufacturing and services jobs, assuming that higher-value-added jobs and, especially, the location of innovation activities are not affected by offshoring.
Veloso, Francisco +2 more
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THE WORKFORCE OF HERZEGOVINA AND ITS INCLUSION IN THE PROCESS OF CROATIAN NATIONAL INTEGRATION [PDF]
Hum, 2013 With the arrival of Austrian-Hungarian monarchy in Bosnia and Herzegovina, transportation infrastructure and communications between settlements started to flourish.
Tihomir Zovko
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source