Results 41 to 50 of about 1,722,169 (314)
FEBS Letters, EarlyView.Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung +6 more
wiley +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
FEBS Letters, EarlyView.Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga +6 more
wiley +1 more source
Orchestrating 5G Network Slices to Support Industrial Internet and to Shape Next-Generation Smart Factories [PDF]
arXiv, 2022 Industry 4.0 aims at shaking the current manufacturing landscape by leveraging the adoption of smart industrial equipment with increased connectivity, sensing, and actuation capabilities. By exploring access to real-time production information and advanced remote control features, servitization of manufacturing firms promises novel added value services
arxiv
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
The socioeconomic performance of small and mediumsized industrial towns: Slovenian perspectives
Moravian Geographical Reports, 2020 The socioeconomic performance of industrial small and medium-sized towns (SMSTs) in comparison to that of non-industrial SMSTs, is subject to evaluation in this paper, to see if the presence of industry has adverse effects on socioeconomic factors.
Bole David, Kozina Jani, Tiran Jernej
doaj +1 more source
Constructing “Pure” and “Applied” Science in Early Francoism
Culture & History Digital Journal, 2021 The paper discusses several appropriations of the categories of “pure” and “applied” science (mainly in chemistry) in early Francoism. At the height of a crusade that criminalized “pure” science as inherently attached to the culture of the Second Spanish
Agustí Nieto-Galan
doaj +1 more source
Forging the Industrial Metaverse -- Where Industry 5.0, Augmented and Mixed Reality, IIoT, Opportunistic Edge Computing and Digital Twins Meet [PDF]
T. M. Fern\'andez-Caram\'es and P. Fraga-Lamas, "Forging the
Industrial Metaverse for Industry 5.0: Where Extended Reality, IIoT,
Opportunistic Edge Computing, and Digital Twins Meet," in IEEE Access, vol.
12, pp. 95778-95819, 2024The Metaverse is a concept that proposes to immerse users into real-time rendered 3D content virtual worlds delivered through Extended Reality (XR) devices like Augmented and Mixed Reality (AR/MR) smart glasses and Virtual Reality (VR) headsets. When the Metaverse concept is applied to industrial environments, it is called Industrial Metaverse, a ...
arxiv +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
The Road to Industry 4.0 and Beyond: A Communications-, Information-, and Operation Technology Collaboration Perspective [PDF]
arXiv, 2022 The fourth industrial revolution, i.e., Industry 4.0, is evolving all around the globe. In this article, we introduce the landscape of Industry 4.0 and beyond empowered by the seamless collaboration of communication technology (CT), information technology (IT), and operation technology (OT), i.e., CIOT collaboration. Specifically, CIOT collaboration is
arxiv
Subpar reporting of pre‐analytical variables in RNA‐focused blood plasma studies
Molecular Oncology, EarlyView.Pre‐analytical variables strongly influence the analysis of extracellular RNA (cell‐free RNA; exRNA) derived from blood plasma. Their reporting is essential to allow interpretation and replication of results. By evaluating 200 exRNA studies, we pinpoint a lack of reporting pre‐analytical variables associated with blood collection, plasma preparation ...
Céleste Van Der Schueren +16 more
wiley +1 more source