Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Exploring the Link between Sustainable Practices and Corporate Performance Across Industries
Business Systems ResearchThe adoption of the Sustainable Development Goals (SDGs) has set a global standard for promoting sustainable practices. However, manufacturing companies need help in adopting these practices due to differences between industries, the need for research ...
Osorio Iris Maria Velez
doaj +1 more source
Evacuation of industry and civilian population to the territory of Kuzbass during the Great Patriotic War [PDF]
Известия Саратовского университета. Новая серия: История. Международные отношенияThe paper examines the process of evacuation of industrial facilities and civilian population to the territory of the Kemerovo region – Kuzbass during the Great Patriotic War.
Starodubtsev, Evgeniy Yurievich
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Technological Innovation and the Role of Smart Surveys in the Industrial Context
Applied SciencesTechnological innovation has significantly transformed the field of statistics, not only in data analysis but also in data collection. Traditional methods based on direct observation have evolved into hybrid approaches that combine passively collected ...
Massimiliano Giacalone +4 more
doaj +1 more source
Car Industry developments – oil industry challenges [PDF]
, 2007 Automotive industry of Europe is one of the greatest economical powers, the „engine of Europe”. It employs directly 2.2 million people and 10 million in related industries and services.
Horváth, Ádám +3 more
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Case-Study: An Industry-Academic Engagement Study of the Brewing and Distilling Sector in Ireland
Irish Journal of Academic Practice, 2023 Industry-academic (I-A) engagement models refer to the collaboration between academic institutions and industry partners to co-create and develop educational programmes that are relevant and responsive to industry needs.
Ciara Walsh +2 more
doaj +1 more source
Balancing simplicity and functionality in designing user-interface for an interactive TV [PDF]
, 2008 Recent computer vision and content-based multimedia techniques such as scene segmentation, face detection, searching through video clips, and video summarisation are potentially useful tools in enhancing the usefulness of an interactive TV (iTV). However,
Ferguson, Paul +8 more
core
The Contemporary Porn Debate - Perceptions of Sexual Health of Porn Actors, The 2013 HIV crisis, and Recognizing the Complexities of the Porn Industry [PDF]
, 2020 Between August 2012 and January 2013, four adult film performers based in California tested positive for HIV which triggered a moratorium on production, and led the state of California to mandate condom usage in the industry under the Safer Sex in the ...
Gooya, Nasreen C.
core +1 more source