Results 41 to 50 of about 1,064,410 (251)
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Cahiers Balkaniques, 2018 This paper aims suggesting an interdisciplinary theoretical frame, providing tools for innovative research focusing on industrial trajectories of Greece and of the whole Mediterranean area.
Christophe Bouneau
doaj +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
A indústria brasileira pós-abertura - uma especialização regressiva?
Economia Aplicada, 2002 This paper discusses the changes in industrial structure in the nineties, after the trade liberalization, specially the thesis of regressive specialization - which can be understood as the gain of importance in lower technology intensity, like ...
Paulo Gonzaga M. de Carvalho
doaj
INSURANCE MARKET REGULATION [PDF]
Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2023 This material defines the basic theoretical knowledge related to the problem of the insurance market. The first part generally characterizes the insurance market, its entities and the factors that influence it.
VĂDUVA MARIA
doaj
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Produtividade na indústria brasileira no passado recente: um estudo dos diferenciais intersetoriais
Economia Aplicada, 2004 This paper discusses the recent evolution of labor productivity in the Brazilian manufacturing and mineral extractive industry. It shows an increase in the productivity gap among industrial sectors from 1985 to 2000.
João Saboia
doaj
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
"KOKSARA BAKAR" – FROM VISION TO DECLINE
Senjski ZbornikThis paper presents the first comprehensive analysis of the business operations of the Bakar Coke Plant, examining the reasons behind its launch, the invested capital and construction investments, key performance indicators through the analysis of coke ...
Bruno Raguž
doaj +1 more source
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source